{"id":"W2737779999","doi":"10.1016/j.bbadis.2017.07.015","title":"Protecting the heart through MK2 modulation, toward a role in diabetic cardiomyopathy and lipid metabolism","year":2017,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Lipid metabolism; Diabetic cardiomyopathy; Diabetes mellitus; Medicine; Bioinformatics; Inflammation; Signal transduction; Cardiomyopathy; Biology; Heart failure; Endocrinology; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005283355,0.0007628645,0.001538816,0.0001444898,0.0002452385,0.0001365467,0.0008353658,0.0003806507,0.000003006674],"category_scores_gemma":[0.0005189574,0.0005941183,0.001063763,0.0002253664,0.0003178067,0.00002385541,0.0006389735,0.0004885143,0.000005715313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002470045,"about_ca_system_score_gemma":0.0005304295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006461442,"about_ca_topic_score_gemma":0.000003401805,"domain_scores_codex":[0.9962438,0.0009818956,0.0007553971,0.001115654,0.0003869245,0.00051635],"domain_scores_gemma":[0.9970341,0.00006078251,0.0007208651,0.001822094,0.0001182547,0.0002439238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003532507,0.0008819097,0.00002414201,0.01509936,0.001851273,0.0000498126,0.0007047981,0.00001764846,0.8466451,0.0005478071,0.0003404889,0.1334844],"study_design_scores_gemma":[0.002185927,0.0006060255,0.003326,0.00722987,0.005141853,0.00004097384,0.0001769463,0.0000877053,0.3526596,0.001052832,0.6241108,0.003381467],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2634697,0.7334074,0.00007752579,0.0003781809,0.0001716218,0.001914974,0.0003943656,0.00002283032,0.0001634499],"genre_scores_gemma":[0.5491347,0.4490207,0.0002485998,0.0001428437,0.0003340345,0.0004665283,0.0005209086,0.0001120379,0.00001973775],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.6237704,"threshold_uncertainty_score":0.999651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03282656073238309,"score_gpt":0.3021240001889688,"score_spread":0.2692974394565857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}