{"id":"W2738044110","doi":"10.1101/167411","title":"ESCRT-Independent Surface Receptor And Transporter Protein Degradation By The ILF Pathway","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Concordia University","keywords":"ESCRT; Endosome; Cell biology; Endocytosis; Biology; Transport protein; Lysosome; Saccharomyces cerevisiae; Vesicular Transport Proteins; Transporter; Receptor; Biochemistry; Yeast; Intracellular; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001686257,0.0003898011,0.0003179344,0.0002870423,0.0002208261,0.0006755361,0.0002116885,0.0004970491,0.001813443],"category_scores_gemma":[0.0002167419,0.0001165821,0.000490869,0.0001561062,0.0002374772,0.0004123042,0.0003456748,0.0005479489,0.0009686476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006213428,"about_ca_system_score_gemma":0.0004414772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009419704,"about_ca_topic_score_gemma":0.0006611847,"domain_scores_codex":[0.9998342,0.00001565863,0.00001271268,0.00004265929,0.00004090117,0.00005378172],"domain_scores_gemma":[0.9998461,0.00001277837,0.00004004117,0.00003551311,0.00003185685,0.00003369876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002979468,0.00003275985,0.002512975,0.0001259723,0.00002907451,0.0006867421,0.0000279848,0.0005212176,0.9861593,0.002170896,0.0007718345,0.006663348],"study_design_scores_gemma":[0.00002411572,0.00005656404,0.009988194,0.00001441787,0.00001608038,0.001962019,0.00004734466,0.005511412,0.9711531,0.001035172,0.01017601,0.0000155567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724753,0.004663716,0.01568198,0.0005037817,0.0001084872,0.00002305623,0.001663338,0.0004042492,0.004476087],"genre_scores_gemma":[0.9866315,0.0009761104,0.004028295,0.00008031206,0.0000154569,0.00001562965,0.001529182,0.00006394187,0.00665965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001813443,"threshold_uncertainty_score":0.006066561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009909973952868538,"score_gpt":0.1964778907678278,"score_spread":0.1865679168149592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}