{"id":"W2738049143","doi":"10.1385/1-59259-087-x:341","title":"Measurement of Intracellular Free Calcium Ion Concentration in Vascular Smooth Muscle Cells: Fluorescence Imaging of Cytosolic Calcium","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Second messenger system; Vascular smooth muscle; Phosphatidylinositol; Intracellular; Inositol trisphosphate; Cell biology; Phospholipase C; Inositol; Endoplasmic reticulum; Diacylglycerol kinase; Cytosol; Calcium; Calcium in biology; Ryanodine receptor; Chemistry; Biology; Receptor; Signal transduction; Endocrinology; Biochemistry; Protein kinase C; Smooth muscle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005054199,0.0001551265,0.0002099654,0.00003866831,0.00004059198,0.00001349673,0.0002166613,0.00009689583,0.00001809314],"category_scores_gemma":[0.00004653721,0.0001599004,0.0001030771,0.00002135773,0.00007727001,0.000005298215,0.00005801301,0.0000886417,3.234848e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002405416,"about_ca_system_score_gemma":0.00006302598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003198248,"about_ca_topic_score_gemma":0.00003420423,"domain_scores_codex":[0.9985885,0.0001509849,0.0003959742,0.0003016801,0.0003188201,0.0002440443],"domain_scores_gemma":[0.9991689,0.000004672615,0.0001714066,0.0004405058,0.000159515,0.00005494543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001653379,0.00005310318,0.00003361188,0.00007915662,0.00002301882,0.000002222387,0.0002009579,0.0002687396,0.9955645,0.001580864,0.00004293186,0.002134392],"study_design_scores_gemma":[0.0007130593,0.00007020411,0.0001469994,0.0000847977,0.00002836075,2.90256e-7,0.00006965122,0.0004239447,0.9944869,0.0001314345,0.003687951,0.0001564278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9474979,0.01351811,0.03389346,0.000005101824,0.0003641837,0.0006635843,0.00001351811,0.00001539568,0.004028719],"genre_scores_gemma":[0.9990694,0.0001111307,0.0006818647,0.00001452223,0.00005207016,0.00001935249,0.000008312052,0.00002040362,0.00002297429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05157144,"threshold_uncertainty_score":0.652055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03399388987539709,"score_gpt":0.2444178888577471,"score_spread":0.21042399898235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}