{"id":"W2738418450","doi":"10.2337/db16-1585","title":"NADPH Oxidase Nox5 Accelerates Renal Injury in Diabetic Nephropathy","year":2017,"lang":"en","type":"article","venue":"Diabetes","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"Medical Research Council; British Heart Foundation; Juvenile Diabetes Research Foundation International","keywords":"Renal injury; Diabetic nephropathy; Medicine; NADPH oxidase; Nephropathy; Internal medicine; Endocrinology; Urology; Diabetes mellitus; Kidney; Oxidative stress","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002364991,0.000139488,0.0001385802,0.00006429711,0.0001916302,0.0001020019,0.0004654906,0.0000955739,0.00005575512],"category_scores_gemma":[0.000750919,0.0001343221,0.0000415266,0.00006460787,0.0001755955,0.00001879991,0.0002518434,0.000137811,0.00005581632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001558044,"about_ca_system_score_gemma":0.00006306228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000142255,"about_ca_topic_score_gemma":0.00001248997,"domain_scores_codex":[0.9988565,0.00006004557,0.0001657581,0.0003909178,0.0001349187,0.0003919018],"domain_scores_gemma":[0.9988753,0.0000156453,0.00008751794,0.0008353975,0.00009659887,0.00008955671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002280603,0.00004750959,0.04702672,0.00001772193,0.00001261154,0.000002631399,0.00001875366,0.00001873109,0.9347948,0.00004037,0.001031262,0.01696613],"study_design_scores_gemma":[0.0003211821,0.0001156089,0.05319611,0.00001812758,0.000002945379,3.393615e-7,0.000009571666,0.00005076433,0.9193841,0.0004068473,0.02631428,0.0001800784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974875,0.0005836192,0.00002232202,0.000634962,0.0001051024,0.000161189,0.00002321102,0.00001133224,0.0009707354],"genre_scores_gemma":[0.9979238,0.0001491464,0.0004286423,0.0002402144,0.0002556385,0.00005780155,0.00008434971,0.00002450933,0.00083592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02528302,"threshold_uncertainty_score":0.5477496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0163391026169467,"score_gpt":0.3067695087805262,"score_spread":0.2904304061635795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}