{"id":"W2738496569","doi":"10.1021/acs.jpcc.7b05271","title":"Chemoradiation Cancer Therapy: Molecular Mechanisms of Cisplatin Radiosensitization","year":2017,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry C","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China","keywords":"Ionizing radiation; DNA damage; Cisplatin; DNA; Agarose gel electrophoresis; Irradiation; Biophysics; DNA repair; Radiosensitizer; Molecular biology; Cancer; Radiation therapy; Chemistry; Cancer research; Biology; Genetics; Biochemistry; Chemotherapy; Medicine; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000246436,0.0004703153,0.0004729378,0.0004661224,0.0002389997,0.0004718553,0.0005368963,0.0008108906,0.001943849],"category_scores_gemma":[0.0002085627,0.000234426,0.0003005069,0.0002360582,0.0003181208,0.0006957657,0.0003696871,0.0006973865,0.0005619036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006605202,"about_ca_system_score_gemma":0.0002154172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002452121,"about_ca_topic_score_gemma":0.0001646346,"domain_scores_codex":[0.9997351,0.00004669701,0.00001467264,0.0000586104,0.00009907314,0.00004594688],"domain_scores_gemma":[0.9999106,0.00001505217,0.00002638527,0.00001243573,0.0000220267,0.00001347569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008892679,0.00005876458,0.0003963278,0.0003628251,0.00002171036,0.0001569342,0.0000443016,0.0004194254,0.9877153,0.002030925,0.0002218484,0.008482779],"study_design_scores_gemma":[0.00001815211,0.000344601,0.006699887,0.0000292469,0.00002134792,0.0008400096,0.00003006221,0.002087092,0.9789346,0.001088582,0.009893107,0.00001329321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8010896,0.1135233,0.06043474,0.002718278,0.0003938906,0.0008525992,0.0007397679,0.0007633602,0.01948448],"genre_scores_gemma":[0.9691361,0.0164292,0.004897539,0.000461221,0.00007349063,0.0002353778,0.0003317113,0.00002608148,0.008409342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001943849,"threshold_uncertainty_score":0.006502867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008581259455160967,"score_gpt":0.2622405211647448,"score_spread":0.2536592617095838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}