{"id":"W2738541296","doi":"10.1016/s0140-6736(17)31917-7","title":"Long-acting intramuscular cabotegravir and rilpivirine in adults with HIV-1 infection (LATTE-2): 96-week results of a randomised, open-label, phase 2b, non-inferiority trial","year":2017,"lang":"en","type":"article","venue":"The Lancet","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":504,"is_retracted":false,"has_abstract":false,"ca_institutions":"GlaxoSmithKline (Canada); Ottawa Hospital","funders":"Bristol-Myers Squibb","keywords":"Rilpivirine; Abacavir; Medicine; Lamivudine; Tolerability; Emtricitabine; Dosing; Internal medicine; Pharmacology; Adverse effect; Viral load; Virology; Human immunodeficiency virus (HIV)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003171953,0.002542546,0.003165114,0.0003866984,0.0004417706,0.001655017,0.001364005,0.003200469,0.01001342],"category_scores_gemma":[0.003042902,0.0009958873,0.002320762,0.0003871514,0.001562127,0.002584287,0.0006148518,0.004716399,0.002282665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008965912,"about_ca_system_score_gemma":0.0008365505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000902955,"about_ca_topic_score_gemma":0.001737752,"domain_scores_codex":[0.9988644,0.000670869,0.00005386562,0.0001622269,0.00006864851,0.0001800171],"domain_scores_gemma":[0.9982724,0.0005922218,0.0003355094,0.000203099,0.00008298207,0.0005138469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9802025,0.003619248,0.0003869238,0.0003167966,0.000535279,0.00004578636,0.00006435248,0.0002444396,0.002403051,0.00007596393,0.0007214578,0.01138434],"study_design_scores_gemma":[0.967898,0.02951932,0.00111652,0.00002828404,0.0002697064,0.00005042483,0.00002776423,0.0002239511,0.0002669412,0.0001313874,0.0004491184,0.00001852805],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865638,0.005233278,0.0006855826,0.001145271,0.0004092255,0.001441192,0.001982201,0.0001837853,0.002355576],"genre_scores_gemma":[0.978314,0.003845639,0.002395426,0.001609906,0.0005692255,0.002942647,0.002722882,0.00009182023,0.007508475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01001342,"threshold_uncertainty_score":0.03349829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04306374395930505,"score_gpt":0.3384009476299573,"score_spread":0.2953372036706522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}