{"id":"W2738901440","doi":"10.1016/j.ebiom.2017.07.020","title":"Safety, Tolerability and Pharmacokinetics of Single Doses of Oxytocin Administered via an Inhaled Route in Healthy Females: Randomized, Single-blind, Phase 1 Study","year":2017,"lang":"en","type":"article","venue":"EBioMedicine","topic":"Maternal and fetal healthcare","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Grand Challenges Canada; Government of Canada","keywords":"Tolerability; Pharmacokinetics; Medicine; Oxytocin; Single blind; Randomized controlled trial; Pharmacology; Internal medicine; Adverse effect","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001625927,0.0002706124,0.001859705,0.0002788928,0.0001014534,0.00001285021,0.0002125941,0.0001112039,0.0000993849],"category_scores_gemma":[0.0003907128,0.0001989639,0.00009291286,0.0001638449,0.0007886642,0.0001228735,0.0001183718,0.0002283657,0.000001266525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000813306,"about_ca_system_score_gemma":0.0001061966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001650383,"about_ca_topic_score_gemma":0.0003954731,"domain_scores_codex":[0.9969134,0.0003233379,0.001541477,0.0004312789,0.0004731739,0.0003173295],"domain_scores_gemma":[0.9976069,0.0002323089,0.0007892298,0.0007501279,0.000235616,0.0003858712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6704048,0.0156581,0.188329,0.003992829,0.00020115,0.0004274099,0.007207049,5.895279e-7,0.04979158,0.00001573117,0.00001123483,0.06396056],"study_design_scores_gemma":[0.8149729,0.03535587,0.1347269,0.001361608,0.0004631646,0.0002157137,0.002226198,0.000661052,0.00937673,0.0001650316,0.0001756117,0.0002992479],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933411,0.0007851527,0.00009883815,0.002276619,0.0002777656,0.00269697,0.00006805541,0.00002250025,0.0004329877],"genre_scores_gemma":[0.9989314,0.0001186094,0.0002711651,0.0002433628,0.0002172104,0.00003265376,0.0000583455,0.00002490904,0.0001023586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1445681,"threshold_uncertainty_score":0.8113511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1117813931300819,"score_gpt":0.4235632467257683,"score_spread":0.3117818535956865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}