{"id":"W2738901440","doi":"10.1016/j.ebiom.2017.07.020","title":"Safety, Tolerability and Pharmacokinetics of Single Doses of Oxytocin Administered via an Inhaled Route in Healthy Females: Randomized, Single-blind, Phase 1 Study","year":2017,"lang":"en","type":"article","venue":"EBioMedicine","topic":"Maternal and fetal healthcare","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Grand Challenges Canada; Government of Canada","keywords":"Tolerability; Pharmacokinetics; Medicine; Oxytocin; Single blind; Randomized controlled trial; Pharmacology; Internal medicine; Adverse effect","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00315397,0.001646382,0.003280868,0.0004517516,0.000520122,0.001085844,0.001242486,0.001671013,0.005989592],"category_scores_gemma":[0.002435998,0.001082175,0.001376698,0.0004678238,0.001659472,0.001278767,0.0004531114,0.002431145,0.001132962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000776711,"about_ca_system_score_gemma":0.002022735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004769283,"about_ca_topic_score_gemma":0.001160352,"domain_scores_codex":[0.9986877,0.0005884757,0.00008391845,0.0003108223,0.0001654468,0.0001636245],"domain_scores_gemma":[0.9981515,0.0003868127,0.0006954746,0.0002144554,0.0001734625,0.0003782831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9112806,0.05700411,0.001204839,0.0007357,0.0005739779,0.00006380477,0.0001477688,0.0003610944,0.01374738,0.00008166375,0.0007543733,0.01404468],"study_design_scores_gemma":[0.5438372,0.4488111,0.003670773,0.00003719017,0.000398651,0.00007444865,0.00004647305,0.0004777944,0.001600396,0.0001071764,0.0009147609,0.00002407314],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844674,0.001494279,0.001300224,0.0002518897,0.0002240653,0.01038771,0.0009974325,0.0001186033,0.0007584608],"genre_scores_gemma":[0.9705733,0.002388867,0.004431386,0.0009538219,0.0005342237,0.01633091,0.001039657,0.00005301914,0.003694762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005989592,"threshold_uncertainty_score":0.02003717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1117813931300819,"score_gpt":0.4235632467257683,"score_spread":0.3117818535956865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}