{"id":"W2739254590","doi":"10.1002/art.39943","title":"Long‐Term Safety and Efficacy of Fulranumab in Patients With Moderate‐to‐Severe Osteoarthritis Pain: A Phase II Randomized, Double‐Blind, Placebo‐Controlled Extension Study","year":2016,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Janssen Research and Development","keywords":"Placebo; Medicine; Osteoarthritis; Double blind; Adverse effect; Randomized controlled trial; Placebo-controlled study; Clinical trial; Physical therapy; Surgery; Internal medicine; Anesthesia","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001090985,0.000543595,0.003140425,0.0005020699,0.000211643,0.00002370787,0.0001215281,0.0002293944,0.0001789153],"category_scores_gemma":[0.0004479297,0.0003627224,0.0002026075,0.0002674215,0.0003190268,0.0002421489,0.0001474593,0.0001947342,0.00002582379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006660174,"about_ca_system_score_gemma":0.0001289054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006491498,"about_ca_topic_score_gemma":0.001091986,"domain_scores_codex":[0.9958755,0.0006820489,0.001383588,0.000899612,0.0004641404,0.0006950975],"domain_scores_gemma":[0.9974674,0.000879277,0.0003571773,0.0006068288,0.0003211602,0.0003681305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7254172,0.003750598,0.06021876,0.00003283885,0.0001846629,0.0002812435,0.001042755,0.00000161532,0.0001366155,0.0002020314,0.0000103896,0.2087213],"study_design_scores_gemma":[0.9551225,0.03436915,0.006704691,0.002407872,0.0002019799,0.0003417735,0.0001200762,0.00001071899,0.0002427374,0.0000662465,0.00001521306,0.0003970554],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856683,0.001750487,0.0003031733,0.0004432778,0.0001916967,0.01139533,0.00004161079,0.00008643722,0.0001196783],"genre_scores_gemma":[0.9978443,0.0007301625,0.0002617662,0.0001079066,0.00001620343,0.0007452972,0.0000742965,0.00006904026,0.0001510406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2297053,"threshold_uncertainty_score":0.9998825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00921728156509756,"score_gpt":0.2518066365497715,"score_spread":0.2425893549846739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}