{"id":"W2739254590","doi":"10.1002/art.39943","title":"Long‐Term Safety and Efficacy of Fulranumab in Patients With Moderate‐to‐Severe Osteoarthritis Pain: A Phase II Randomized, Double‐Blind, Placebo‐Controlled Extension Study","year":2016,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Janssen Research and Development","keywords":"Placebo; Medicine; Osteoarthritis; Double blind; Adverse effect; Randomized controlled trial; Placebo-controlled study; Clinical trial; Physical therapy; Surgery; Internal medicine; Anesthesia","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00330128,0.001519715,0.002359352,0.0003278202,0.0004796988,0.0007014003,0.0007843513,0.001644873,0.003179519],"category_scores_gemma":[0.001834064,0.0005907225,0.001551054,0.0002801447,0.000884552,0.00079461,0.0003131788,0.001934112,0.0006185123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003387772,"about_ca_system_score_gemma":0.001006966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002817887,"about_ca_topic_score_gemma":0.0005969597,"domain_scores_codex":[0.9992625,0.0003936763,0.00005952068,0.00009905314,0.00007928719,0.0001058986],"domain_scores_gemma":[0.9989202,0.0002650589,0.0002772389,0.0001079795,0.00009674904,0.000332907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9272766,0.02464329,0.00170075,0.0007885721,0.0005922439,0.00009051769,0.0001251211,0.0002961441,0.01339088,0.00006464388,0.0006853017,0.03034603],"study_design_scores_gemma":[0.826049,0.1666596,0.005056489,0.00003082589,0.0002668251,0.00009417557,0.0000192909,0.0002876808,0.0008496338,0.00004220123,0.0006285732,0.00001575036],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910567,0.003141743,0.0008083358,0.0002346096,0.0001998138,0.003329735,0.0004095868,0.00006682293,0.0007527257],"genre_scores_gemma":[0.989638,0.001721741,0.001555694,0.0007258545,0.000330417,0.004351169,0.0005689923,0.00001412869,0.001093916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00330128,"threshold_uncertainty_score":0.01745903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00921728156509756,"score_gpt":0.2518066365497715,"score_spread":0.2425893549846739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}