{"id":"W2739307379","doi":"10.14814/phy2.13307","title":"Regulation of the autophagy system during chronic contractile activity-induced muscle adaptations","year":2017,"lang":"en","type":"article","venue":"Physiological Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Downregulation and upregulation; Skeletal muscle; TFEB; Mitochondrial biogenesis; Lysosome; Cell biology; Mitochondrion; Biology; LAMP1; Endocrinology; Organelle biogenesis; Internal medicine; Chemistry; Biogenesis; Medicine; Biochemistry; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001360847,0.0001735077,0.0003110752,0.0001667381,0.0001385634,0.0001506279,0.00009089492,0.0002371819,0.0005290993],"category_scores_gemma":[0.00008507373,0.0000893438,0.0002197584,0.00009059569,0.0002567143,0.0001408936,0.0002611091,0.0003780624,0.00008550601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001578909,"about_ca_system_score_gemma":0.0001460708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003322648,"about_ca_topic_score_gemma":0.0008334391,"domain_scores_codex":[0.9999037,0.00001773494,0.000008006038,0.00002112942,0.00001393734,0.00003555399],"domain_scores_gemma":[0.9999269,0.000008250575,0.00002211347,0.000007452182,0.00001206084,0.00002311273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006401044,0.00004300102,0.001437935,0.00005012334,0.00001044179,0.00007613158,0.00002905537,0.0000312743,0.99613,0.00002363941,0.0000259162,0.001502419],"study_design_scores_gemma":[0.00007790028,0.004321766,0.5249602,0.00006168028,0.00009005712,0.0004552721,0.0004372344,0.001394515,0.4659831,0.0002686359,0.001924234,0.00002548209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975827,0.001329552,0.0005896136,0.00004365032,0.00001399328,0.00001573784,0.00007985799,0.00001138442,0.0003334268],"genre_scores_gemma":[0.998285,0.0005431844,0.0003230318,0.00004227,0.00001059093,0.00005482815,0.0001359319,0.000003159487,0.0006019214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005290993,"threshold_uncertainty_score":0.001770079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03794225389769898,"score_gpt":0.3056194333472855,"score_spread":0.2676771794495866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}