{"id":"W2739401537","doi":"10.2147/ceg.s121841","title":"Children’s International Polyposis (CHIP) study: a randomized, double-blind, placebo-controlled study of celecoxib in children with familial adenomatous polyposis","year":2017,"lang":"en","type":"article","venue":"Clinical and Experimental Gastroenterology","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Global Affairs Canada","funders":"Cliniques Universitaires Saint-Luc; Chinese University of Hong Kong; Universitair Ziekenhuis Gent; Rush University; Cincinnati Children's Hospital Medical Center; Memorial Sloan-Kettering Cancer Center; Cleveland Clinic; Vanderbilt University; Queen Mary University of London; University of Nebraska Medical Center; Vanderbilt University Medical Center; Pfizer","keywords":"Medicine; Celecoxib; Placebo; Familial adenomatous polyposis; Colorectal cancer; Internal medicine; Gastroenterology; Adverse effect; Randomization; Randomized controlled trial; Malignancy; Cancer; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001725842,0.001121961,0.002222296,0.0003968042,0.000451181,0.0005877001,0.0005448387,0.001398999,0.002850395],"category_scores_gemma":[0.001685273,0.0005952382,0.001448696,0.0003429529,0.0009626513,0.0004534236,0.0003194082,0.001699259,0.0003033763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006430804,"about_ca_system_score_gemma":0.001793382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001535184,"about_ca_topic_score_gemma":0.003361871,"domain_scores_codex":[0.9990777,0.0005382245,0.00006306839,0.0001192253,0.0001156267,0.00008604836],"domain_scores_gemma":[0.998861,0.0002767776,0.0003274379,0.00005691169,0.00007907187,0.0003988937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9337537,0.01349318,0.01001464,0.002405724,0.001788833,0.000235543,0.0001121117,0.0002978421,0.007319993,0.0002116077,0.001450549,0.02891628],"study_design_scores_gemma":[0.8752204,0.1076573,0.01394254,0.00007387558,0.0006291608,0.0001600961,0.0000281248,0.0001248961,0.0005656893,0.00003270091,0.001554124,0.00001114296],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842557,0.008365957,0.0003870545,0.0005658943,0.0002807573,0.004057565,0.0008990914,0.00003839388,0.00114951],"genre_scores_gemma":[0.9805261,0.006634017,0.002511141,0.001221697,0.0005404462,0.006149666,0.0009393213,0.00001393084,0.001463695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002850395,"threshold_uncertainty_score":0.009535491,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02712597195127716,"score_gpt":0.3448648757882689,"score_spread":0.3177389038369917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}