{"id":"W2739477427","doi":"10.1101/126458","title":"ETV4 and AP1 transcription factors form multivalent interactions with three sites on the MED25 activator-interacting domain","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre","funders":"British Columbia Knowledge Development Fund; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; National Institutes of Health; University of Utah; Michael Smith Health Research BC; Huntsman Cancer Institute; Huntsman Cancer Foundation; Howard Hughes Medical Institute","keywords":"AP-1 transcription factor; Enhancer; Transcription factor; Biology; Activator (genetics); Cell biology; Mediator; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001566269,0.000361693,0.0002229193,0.0003046574,0.0003664901,0.0004932078,0.0005395102,0.0002668005,0.003995231],"category_scores_gemma":[0.0002334335,0.0002340441,0.0004809221,0.0002093169,0.0002647364,0.0002935001,0.0008399752,0.0004362939,0.001376892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007592877,"about_ca_system_score_gemma":0.0001492651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005954998,"about_ca_topic_score_gemma":0.0006987759,"domain_scores_codex":[0.9996992,0.00004280659,0.00001453954,0.00009915428,0.00007795486,0.00006638646],"domain_scores_gemma":[0.9998276,0.00002269967,0.00004310394,0.00001896853,0.00001763898,0.00006990606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002495186,0.00002634158,0.001687801,0.00004966281,0.00003574568,0.00009925806,0.00002069686,0.0001668737,0.9947206,0.0004731338,0.0001193413,0.002351208],"study_design_scores_gemma":[0.00005344489,0.0002350022,0.03456748,0.00002054915,0.00006690143,0.0009205275,0.0001431045,0.005702172,0.9434157,0.0007129173,0.01413783,0.00002443227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866077,0.002091961,0.00825283,0.00006608077,0.00004348525,0.00002265614,0.0002223719,0.00009307195,0.002599801],"genre_scores_gemma":[0.9925458,0.000180228,0.002505389,0.00003751167,0.000008983075,0.00001994868,0.0004645975,0.0000106174,0.00422693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003995231,"threshold_uncertainty_score":0.01336539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01765060086987031,"score_gpt":0.2292562169290956,"score_spread":0.2116056160592253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}