{"id":"W2739480369","doi":"10.1158/1538-7445.am2017-4196","title":"Abstract 4196: Anti-tumor activity of a TAM kinase-targeting compound in CT-26 syngeneic mouse model","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SignalChem (Canada)","funders":"","keywords":"Tumor microenvironment; Cancer research; Immune system; Kinase; Receptor tyrosine kinase; Cancer; CD8; Immune checkpoint; Metastasis; Biology; Medicine; Immunotherapy; Immunology; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002635153,0.001044681,0.0005617756,0.0008559271,0.0002471327,0.000264191,0.0004317278,0.0007896334,0.002887069],"category_scores_gemma":[0.00009344476,0.0002871742,0.0005451262,0.0003442224,0.0004550989,0.0004024238,0.0001438778,0.001559184,0.0008446263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004354497,"about_ca_system_score_gemma":0.000390495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00109007,"about_ca_topic_score_gemma":0.001156742,"domain_scores_codex":[0.999772,0.00002953624,0.00001892272,0.00005917918,0.0000562095,0.00006404345],"domain_scores_gemma":[0.999806,0.00001892158,0.00005528507,0.00002213813,0.00001594774,0.00008169723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001012786,0.0004949962,0.00009408707,0.00006279438,0.000009308263,0.0001662204,0.00001627535,0.0002043216,0.9963988,0.0001578071,0.0001737685,0.001208822],"study_design_scores_gemma":[0.0002040637,0.005990004,0.001314758,0.00001284437,0.0000295085,0.00039923,0.00002235872,0.0009093893,0.9888247,0.00005650079,0.002228585,0.00000817949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883419,0.001873041,0.00241434,0.0004430758,0.0001549113,0.000224752,0.002793891,0.0003368469,0.003417204],"genre_scores_gemma":[0.9802453,0.001714675,0.002982081,0.0001590157,0.00004520134,0.0003265758,0.002444617,0.00005545832,0.01202698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002887069,"threshold_uncertainty_score":0.009658217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.106444971333878,"score_gpt":0.3972439327358291,"score_spread":0.2907989614019511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}