{"id":"W2739570343","doi":"10.1111/vcp.12526","title":"Feline leukocyte adhesion (<scp>CD</scp>18) deficiency caused by a deletion in the integrin β<sub>2</sub>(<i><scp>ITGB</scp>2</i>) gene","year":2017,"lang":"en","type":"article","venue":"Veterinary Clinical Pathology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Optech (Canada)","funders":"National Institutes of Health; Fundação Luso-Americana para o Desenvolvimento; Leidos; National Cancer Institute; University of Pennsylvania","keywords":"Leukocyte adhesion deficiency; Immunology; Biology; Exon; Molecular biology; Neutrophilia; Leukocytosis; CD18; Gene; Genetics; Flow cytometry; Integrin alpha M","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004729076,0.0005658555,0.001161798,0.0003605286,0.0005208503,0.0001281137,0.001418062,0.0009732489,0.00003257009],"category_scores_gemma":[0.01460589,0.0004275867,0.0005162039,0.0003863098,0.001162496,0.0001949917,0.001026643,0.002403466,0.0008384939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001854551,"about_ca_system_score_gemma":0.0002721177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005701585,"about_ca_topic_score_gemma":0.00003810961,"domain_scores_codex":[0.9924543,0.00212388,0.001761541,0.001465936,0.0009152452,0.001279046],"domain_scores_gemma":[0.9924359,0.003685712,0.0006590844,0.002442284,0.0002903955,0.0004866078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002466362,0.0014924,0.01818135,0.0001095145,0.00002793314,0.01003775,0.0002853389,0.000003743297,0.9338961,0.00002047201,0.01583525,0.01986351],"study_design_scores_gemma":[0.01094708,0.02030712,0.7548355,0.0003261828,0.0002015316,0.004053858,0.0007618498,0.001030486,0.1466837,0.0005485198,0.0599837,0.0003204649],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928694,0.001057628,0.0005757932,0.001269836,0.0006976964,0.001267763,0.00003476174,0.0001200728,0.002106991],"genre_scores_gemma":[0.992238,0.003150936,0.0007858098,0.002161392,0.0005071358,0.0002027804,0.0001779207,0.0001002742,0.0006756852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7872124,"threshold_uncertainty_score":0.9999394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1041038436883489,"score_gpt":0.3926597137287798,"score_spread":0.2885558700404309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}