{"id":"W2739577140","doi":"10.1158/1538-7445.am2017-lb-055","title":"Abstract LB-055: Overall survival and safety experience from an expanded access program (EAP) of nivolumab (NIVO) for patients with advanced melanoma (MEL) who progressed after prior ipilimumab (IPI) treatment","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; London Health Sciences Centre; McMaster University","funders":"","keywords":"Medicine; Ipilimumab; Nivolumab; Internal medicine; Expanded access; Adverse effect; Oncology; Melanoma; Stage (stratigraphy); Immunotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000814511,0.0001929343,0.0003044809,0.0001928103,0.0002684867,0.0006555961,0.0002806165,0.0002612822,0.002614049],"category_scores_gemma":[0.0010702,0.00007007522,0.0003787146,0.0002699158,0.0002032825,0.0002880303,0.0004464903,0.0006228541,0.0005167489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001006326,"about_ca_system_score_gemma":0.001020766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002482919,"about_ca_topic_score_gemma":0.003430092,"domain_scores_codex":[0.999667,0.0001619169,0.00001959609,0.00005399344,0.00004914986,0.00004836683],"domain_scores_gemma":[0.9993485,0.0001202493,0.0001156415,0.00004657588,0.00007503369,0.0002939308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.2030551,0.02541147,0.1773183,0.0005154181,0.0007327197,0.0008429664,0.0006134294,0.00202289,0.02239929,0.0003524174,0.01232909,0.5544069],"study_design_scores_gemma":[0.05370829,0.3861467,0.5053313,0.0002149095,0.001290109,0.001948101,0.0005540943,0.004595767,0.01076313,0.0003408861,0.0350518,0.00005502367],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947752,0.0008006998,0.000287601,0.0001930823,0.00001669694,0.0001961773,0.001502257,0.00003376804,0.002194517],"genre_scores_gemma":[0.9949635,0.000314708,0.0002874522,0.0003253082,0.00003326854,0.0001511313,0.002879552,0.000008229893,0.00103692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002614049,"threshold_uncertainty_score":0.008744895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06117101554433939,"score_gpt":0.4384892932454799,"score_spread":0.3773182777011405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}