{"id":"W2739855284","doi":"10.1158/1538-7445.am2017-8","title":"Abstract 8: Anandamide reduces cell migration, invasion, and induces apoptosis in an <i>in vitro</i> model of prostate cancer","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"DU145; LNCaP; Cannabinoid receptor; Anandamide; Cancer research; Cancer; Cancer cell; Endocannabinoid system; Apoptosis; Fatty acid amide hydrolase; Angiogenesis; Prostate cancer; Cell growth; Biology; Paracrine signalling; Receptor; Medicine; Internal medicine; Agonist; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001404382,0.0004945929,0.000343263,0.0003294444,0.0002138033,0.0002338014,0.0003207429,0.0003144724,0.004247256],"category_scores_gemma":[0.00007889729,0.0001599856,0.0006237532,0.0002316804,0.000175561,0.0002140857,0.0001151957,0.000986888,0.0006554311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003208267,"about_ca_system_score_gemma":0.0005425127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002482423,"about_ca_topic_score_gemma":0.003488369,"domain_scores_codex":[0.9998502,0.00002287243,0.00001713963,0.00002504304,0.00004256585,0.0000421958],"domain_scores_gemma":[0.9999048,0.00001227448,0.00002276831,0.00001003241,0.00002137574,0.00002886982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001142176,0.0007850826,0.0003275746,0.0003358456,0.0000293714,0.0001115953,0.00003596075,0.0001788524,0.9919242,0.0001305969,0.0008881587,0.004110629],"study_design_scores_gemma":[0.0001068936,0.005951473,0.003891406,0.00002699,0.00005140715,0.0002412582,0.00004223861,0.0005527916,0.985782,0.000042335,0.003301915,0.000009186285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976999,0.00515547,0.0034755,0.0006683162,0.000438614,0.0002232992,0.003585709,0.0003833709,0.009070656],"genre_scores_gemma":[0.971284,0.004086052,0.003281578,0.0002604161,0.00006500029,0.0002372765,0.003904426,0.00003858404,0.01684274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004247256,"threshold_uncertainty_score":0.01420844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08127629373602889,"score_gpt":0.3967918460242559,"score_spread":0.315515552288227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}