{"id":"W2740436806","doi":"10.1182/blood.v128.22.4124.4124","title":"The Role of UBR5 Mutations in the Pathogenesis of Mantle CELL Lymphoma","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Biology; Immunoprecipitation; Mutant; Mantle cell lymphoma; Cancer research; Ubiquitin ligase; Mutation; Proteome; Molecular biology; Genetics; Gene; Ubiquitin; Lymphoma; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002353586,0.0002954916,0.0001330841,0.0005419716,0.0001012999,0.0002726956,0.0002221184,0.0003279424,0.0007019834],"category_scores_gemma":[0.0001494789,0.0001144996,0.0001673881,0.000220096,0.0002251873,0.000171972,0.0002189037,0.0002117512,0.0001739849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002300391,"about_ca_system_score_gemma":0.00008007182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003285614,"about_ca_topic_score_gemma":0.0002410305,"domain_scores_codex":[0.9998989,0.00001835977,0.00001123058,0.00002804471,0.00002482705,0.0000187124],"domain_scores_gemma":[0.9999363,0.00001022369,0.00003052589,0.000006915237,0.000005227317,0.00001078366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005093399,0.00006415671,0.05784081,0.0001131374,0.00005311104,0.002211518,0.00006046557,0.0002994315,0.927761,0.0002129277,0.0001247208,0.01074949],"study_design_scores_gemma":[0.00006130515,0.0007169333,0.5369827,0.00004926276,0.0002186608,0.01864791,0.0002007117,0.004424193,0.4343364,0.000462337,0.003883826,0.00001587251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972169,0.001595837,0.0006613436,0.00003936731,0.000003598874,0.000006579879,0.0000828763,0.00003733872,0.0003561011],"genre_scores_gemma":[0.9993475,0.0002186146,0.0002717249,0.00001488579,0.000002082437,0.000001584416,0.00006127558,0.000002206524,0.00008022862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007019834,"threshold_uncertainty_score":0.002348423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005944076977064536,"score_gpt":0.2031671674382162,"score_spread":0.1972230904611517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}