{"id":"W2741168976","doi":"10.1128/jvi.00812-17","title":"Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate Egress","year":2017,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Cancer Prevention and Research Institute of Texas","keywords":"VP40; Ubiquitin ligase; Biology; WW domain; Cell biology; Ubiquitin; Mutant; Filoviridae; Ebola virus; Molecular biology; Virology; Virus; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000099129,0.0002894712,0.0001756695,0.0002062377,0.000195494,0.0003096528,0.0001617383,0.0002113448,0.001171987],"category_scores_gemma":[0.0000871717,0.0001503052,0.0002600776,0.0001454366,0.0001354097,0.0001494707,0.0002847969,0.0003233523,0.0005868876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004416879,"about_ca_system_score_gemma":0.0001032262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000304254,"about_ca_topic_score_gemma":0.0004809278,"domain_scores_codex":[0.9998927,0.00001352618,0.00000729046,0.00002889247,0.00002536139,0.00003214004],"domain_scores_gemma":[0.9999491,0.000008981808,0.00001469415,0.000004892564,0.000006991451,0.00001531595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005361041,0.00001017902,0.0002827468,0.00002403407,0.000004931139,0.00006621303,0.000007650299,0.00004219463,0.9988732,0.00006979977,0.00004468071,0.000520815],"study_design_scores_gemma":[0.00000809284,0.00007018276,0.01254565,0.000005550216,0.00001170985,0.0003878589,0.00002952631,0.001881176,0.9825423,0.0000603379,0.002453203,0.000004419178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950297,0.001827132,0.001603808,0.00007221803,0.00001602923,0.00001219228,0.0003422439,0.00004410593,0.00105257],"genre_scores_gemma":[0.994534,0.0007457681,0.00100647,0.00005588937,0.00000732195,0.0000170556,0.0007797332,0.00001466529,0.002839114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001171987,"threshold_uncertainty_score":0.003920674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02842967101761945,"score_gpt":0.3853730333870079,"score_spread":0.3569433623693885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}