{"id":"W2741228770","doi":"10.1016/j.intimp.2017.06.031","title":"IL-27 induces a pro-inflammatory response in human fetal membranes mediating preterm birth","year":2017,"lang":"en","type":"article","venue":"International Immunopharmacology","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Key Research and Development Program of China; Specialized Research Fund for the Doctoral Program of Higher Education of China; Program for Innovation Team Building at Institutions of Higher Education in Chongqing; National Natural Science Foundation of China","keywords":"Fetus; CXCL10; Premature rupture of membranes; Fetal membrane; PI3K/AKT/mTOR pathway; Proinflammatory cytokine; Cytokine; Medicine; MAPK/ERK pathway; Inflammation; Immunology; Signal transduction; Chemokine; Biology; Pregnancy; Cell biology; Placenta","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004096743,0.0003048451,0.0002111547,0.0004012209,0.0003327923,0.0004749611,0.0001616628,0.0002947646,0.003686301],"category_scores_gemma":[0.0005773459,0.0001668507,0.0002901951,0.000132009,0.0004067212,0.0002236787,0.0004330744,0.0007364872,0.0005828158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002981156,"about_ca_system_score_gemma":0.0003458388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005144861,"about_ca_topic_score_gemma":0.0003112422,"domain_scores_codex":[0.9997622,0.00008418487,0.00001567751,0.00002420456,0.00003556883,0.00007813662],"domain_scores_gemma":[0.9998424,0.00004675872,0.00001801798,0.00002538187,0.00003022594,0.00003710472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003789776,0.0002193346,0.003864308,0.0001619898,0.00002227866,0.00140799,0.0003679717,0.0002054168,0.981295,0.0008336758,0.0002812375,0.00755102],"study_design_scores_gemma":[0.0002411738,0.002132993,0.05608118,0.0001196956,0.0001128633,0.003074898,0.001704724,0.001383657,0.9251749,0.001518259,0.008434958,0.00002071109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932305,0.002265593,0.001070164,0.0002824826,0.0001050778,0.00005067392,0.0001646112,0.00001865993,0.002812304],"genre_scores_gemma":[0.9961808,0.001055715,0.0004919542,0.0001156115,0.0000576984,0.00004306743,0.0002421729,0.000008600673,0.001804407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003686301,"threshold_uncertainty_score":0.0123319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02384778423688637,"score_gpt":0.3434237644648467,"score_spread":0.3195759802279604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}