{"id":"W2741381450","doi":"10.1158/1538-7445.am2017-4419","title":"Abstract 4419: HER2 expression and 17β-estradiol induce ACSL4 expression in estrogen receptor positive mammary carcinoma cells","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"","keywords":"Gene silencing; Arachidonic acid; Eicosapentaenoic acid; Biology; Polyunsaturated fatty acid; Endocrinology; Estrogen receptor; Internal medicine; Cell growth; Fatty acid; Biochemistry; Cancer; Breast cancer; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001306934,0.0002907912,0.0003277567,0.0002384012,0.000172013,0.0002848073,0.0001605544,0.0002088929,0.004154144],"category_scores_gemma":[0.00008320632,0.0001599411,0.000377261,0.0002930578,0.0001825079,0.0001450251,0.0002037657,0.0004544024,0.001327199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004184696,"about_ca_system_score_gemma":0.0002644493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00143844,"about_ca_topic_score_gemma":0.001110847,"domain_scores_codex":[0.9998106,0.00002379773,0.00002023201,0.00003247556,0.00005618225,0.00005676049],"domain_scores_gemma":[0.9999065,0.00001659333,0.00001853084,0.00001506039,0.00001942424,0.00002390178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001316502,0.00003666858,0.0001370562,0.00002099081,0.000003888753,0.00004059163,0.00001221181,0.00001776757,0.9990081,0.00003479484,0.00006366744,0.0004925992],"study_design_scores_gemma":[0.00002233569,0.0002996494,0.004705771,0.000003654905,0.00001050746,0.0001515322,0.00004059167,0.000392199,0.9905364,0.00002196946,0.003812013,0.00000342814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913428,0.001735158,0.001549915,0.0002484608,0.00009890649,0.00004248296,0.001852225,0.0001042702,0.003025821],"genre_scores_gemma":[0.9657855,0.001595951,0.002375367,0.000200085,0.00003469904,0.0001464571,0.004937093,0.00006170035,0.02486323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004154144,"threshold_uncertainty_score":0.013897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0493168619917882,"score_gpt":0.3733886735445674,"score_spread":0.3240718115527792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}