{"id":"W2741530611","doi":"10.1007/978-3-319-55780-9_13","title":"Newborn Screening for Hereditary Tyrosinemia Type I in Québec: Update","year":2017,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Newborn screening; Tyrosinemia; Medicine; Pediatrics; Population; Genetic disorder; Tyrosine; Internal medicine; Chemistry; Disease; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00132649,0.0008034261,0.001500385,0.002791589,0.0003611938,0.001013645,0.001366276,0.001286288,0.00448115],"category_scores_gemma":[0.002825193,0.0002223568,0.0006506203,0.002406177,0.0005253702,0.0006620074,0.0005535146,0.001214446,0.0006483059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004591708,"about_ca_system_score_gemma":0.008811996,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.2068497,"about_ca_topic_score_gemma":0.3631844,"domain_scores_codex":[0.9995822,0.00005891469,0.00006096713,0.00006070119,0.0001806815,0.00005644349],"domain_scores_gemma":[0.9983081,0.0005653912,0.0001670786,0.00002444952,0.0007639048,0.0001711318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001052912,0.00003905016,0.003116154,0.007501943,0.0001547851,0.0007092966,0.00007571146,0.0002548917,0.000453712,0.001185155,0.1071533,0.8792506],"study_design_scores_gemma":[0.00006597151,0.00006141121,0.01017356,0.01472218,0.0006472504,0.003010871,0.0001489166,0.0002140186,0.0003487151,0.0005692884,0.9699951,0.00004269026],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002061312,0.9972004,0.0001441348,0.0008396367,0.0003749405,0.000006288978,0.0001592057,0.00001428235,0.001054997],"genre_scores_gemma":[0.001831146,0.9954414,0.0003939082,0.0008038816,0.0004024329,0.00001066242,0.0002571046,0.00000437147,0.0008549941],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7931503,"threshold_uncertainty_score":0.4112914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08292377644025682,"score_gpt":0.4400456530816113,"score_spread":0.3571218766413544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}