{"id":"W2741548282","doi":"","title":"Metformin inhibits survival, migration, and vascular endothelial growth factor production in uveal melanoma cells","year":2017,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Mechanisms of cancer metastasis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Metformin; Vascular endothelial growth factor; Melanoma; Cancer research; Medicine; Vascular endothelial growth factor C; Internal medicine; VEGF receptors; Vascular endothelial growth factor A; Oncology; Endocrinology; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009785439,0.0002207595,0.0002456212,0.0001343255,0.0004857076,0.0001046129,0.0005276703,0.0001385044,0.00002024367],"category_scores_gemma":[0.001827709,0.0002052106,0.00004654674,0.00017647,0.002530402,0.00008198311,0.0003449841,0.0001415951,0.000007582574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004261946,"about_ca_system_score_gemma":0.0003151563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003832179,"about_ca_topic_score_gemma":0.0001561632,"domain_scores_codex":[0.9979839,0.0001733131,0.0002607788,0.0008467681,0.0003314099,0.0004038391],"domain_scores_gemma":[0.9988506,0.00002486087,0.0002496427,0.0004408789,0.0002338318,0.000200149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002359462,0.00003884075,0.03206971,0.00001041167,0.00001473499,0.00001115649,0.0001820314,0.000003190769,0.9671778,0.0001000155,0.0000129202,0.0003556062],"study_design_scores_gemma":[0.0003255925,0.000455239,0.07777953,0.00001500829,0.000009272856,0.00004493216,0.00007833215,0.00002155201,0.9195141,0.001439898,0.0001115335,0.000204972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998414,0.0001128039,0.00001495417,0.0003160549,0.0005305125,0.0003252726,0.00002336293,0.000007710023,0.0002553706],"genre_scores_gemma":[0.9978039,0.00006730711,0.001736668,0.00005476976,0.0001596952,0.0000455083,0.000008568196,0.0000149768,0.0001086283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04766365,"threshold_uncertainty_score":0.9323373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03417136272298841,"score_gpt":0.3146969321831251,"score_spread":0.2805255694601367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}