{"id":"W2741548282","doi":"","title":"Metformin inhibits survival, migration, and vascular endothelial growth factor production in uveal melanoma cells","year":2017,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Mechanisms of cancer metastasis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Metformin; Vascular endothelial growth factor; Melanoma; Cancer research; Medicine; Vascular endothelial growth factor C; Internal medicine; VEGF receptors; Vascular endothelial growth factor A; Oncology; Endocrinology; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002017094,0.0002836066,0.0002844667,0.0002722729,0.0002899805,0.0003457076,0.0002035387,0.0002658876,0.0012174],"category_scores_gemma":[0.0001673231,0.000160332,0.0003270613,0.0002457748,0.0001875637,0.0002099013,0.0001814297,0.0006437129,0.0002729378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000336941,"about_ca_system_score_gemma":0.0004819053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002263018,"about_ca_topic_score_gemma":0.002921982,"domain_scores_codex":[0.9997976,0.00004332896,0.0000248477,0.00001688937,0.000041463,0.00007589118],"domain_scores_gemma":[0.9999028,0.00002178053,0.00002095224,0.00001559537,0.00001152653,0.00002723145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001754762,0.0002770568,0.001078089,0.00007597977,0.00001899695,0.000159018,0.00005107812,0.0001754889,0.9912316,0.0002077878,0.0003636602,0.004606361],"study_design_scores_gemma":[0.0001856293,0.001963975,0.01178532,0.00001098938,0.00004813257,0.000219361,0.0001361488,0.001830371,0.9787707,0.0000882653,0.004948793,0.00001216332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969717,0.001256133,0.0003977813,0.0001429087,0.00005965112,0.00001346687,0.000214486,0.00002935606,0.0009144307],"genre_scores_gemma":[0.9948714,0.001162964,0.0005190538,0.00005985208,0.00001699359,0.00003798028,0.0004866497,0.000007543154,0.002837654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002263018,"threshold_uncertainty_score":0.004499674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03417136272298841,"score_gpt":0.3146969321831251,"score_spread":0.2805255694601367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}