{"id":"W2741674151","doi":"10.1158/1538-7445.am2017-3758","title":"Abstract 3758: The efficacy of CD133 BiTEs and CAR-T cells in preclinical model of glioblastoma","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McMaster University","funders":"","keywords":"Antigen; Population; Flow cytometry; Antibody; Peripheral blood mononuclear cell; Immunophenotyping; Cancer research; Monoclonal antibody; Immunology; Chimeric antigen receptor; Medicine; CD3; Biology; Immunotherapy; CD8; In vitro; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000288335,0.0007646359,0.000685316,0.0004644498,0.000168615,0.0002844493,0.0003553419,0.000519214,0.002291747],"category_scores_gemma":[0.0001258384,0.0001856845,0.0003615844,0.0002636967,0.0003374271,0.0003096921,0.0001807618,0.00147217,0.0004941178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004379502,"about_ca_system_score_gemma":0.0006035042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002849949,"about_ca_topic_score_gemma":0.002389067,"domain_scores_codex":[0.9997672,0.00002884056,0.00001764619,0.00004264436,0.00005628298,0.00008741004],"domain_scores_gemma":[0.9999233,0.000008194354,0.00001099807,0.0000088908,0.00001119454,0.00003734587],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002678226,0.002723019,0.0002012448,0.0002330616,0.00004692829,0.0001041302,0.0001049305,0.0007303057,0.9804166,0.0004586591,0.0009975967,0.01130535],"study_design_scores_gemma":[0.0004817169,0.03256404,0.002167118,0.00002330299,0.0001161568,0.000188361,0.00008950548,0.003060682,0.9566689,0.000194958,0.004425001,0.00002016526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927568,0.001296624,0.00188912,0.0002552677,0.0001740753,0.0001769675,0.000753045,0.00024777,0.002450336],"genre_scores_gemma":[0.9910303,0.0009918938,0.001473107,0.000111212,0.00002962508,0.0002306201,0.001026181,0.00003218828,0.005074841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002849949,"threshold_uncertainty_score":0.007666647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1939765211105642,"score_gpt":0.4941647106937867,"score_spread":0.3001881895832225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}