{"id":"W2741892369","doi":"10.1158/1538-7445.am2017-5202","title":"Abstract 5202: Additive benefits of radium-223 dichloride and bortezomib combination in a syngeneic 5TGM1 multiple myeloma mouse model","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Weyerhauser (Canada)","funders":"","keywords":"Bortezomib; Multiple myeloma; Medicine; Osteoclast; Prostate cancer; Osteoblast; Bone marrow; In vivo; Cancer research; Osteolysis; Cancer; Urology; Nuclear medicine; Pathology; Internal medicine; Chemistry; In vitro; Surgery; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002692981,0.001048718,0.001060686,0.001025646,0.0002670962,0.0005460047,0.0005202006,0.0007119923,0.001898564],"category_scores_gemma":[0.00009432733,0.0003352258,0.0007294158,0.0004398039,0.0003578015,0.0003991498,0.0002255802,0.001558608,0.000604861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004087653,"about_ca_system_score_gemma":0.0004007564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001411465,"about_ca_topic_score_gemma":0.001840068,"domain_scores_codex":[0.999576,0.00006511575,0.00003655939,0.00009243481,0.0001390546,0.00009073059],"domain_scores_gemma":[0.9998302,0.00001432509,0.00004545815,0.00001986084,0.00001301005,0.00007718347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002045396,0.0008119069,0.0001850019,0.00008463011,0.00003409714,0.00009535395,0.00001869134,0.0001681406,0.9934487,0.0001078756,0.0002500236,0.002750195],"study_design_scores_gemma":[0.0005833137,0.01266993,0.003148594,0.00002245621,0.0002257204,0.0005817129,0.00005175098,0.001094666,0.9760818,0.00008001434,0.005439353,0.00002063363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885322,0.004031357,0.001755509,0.0003856844,0.0002489602,0.0001495066,0.001576143,0.0003582567,0.002962271],"genre_scores_gemma":[0.9828061,0.00302916,0.003187726,0.0002570237,0.0001032385,0.0002420583,0.002445812,0.00009238579,0.007836557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001898564,"threshold_uncertainty_score":0.006351292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1437467403986456,"score_gpt":0.4474921977529047,"score_spread":0.3037454573542591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}