{"id":"W2742175177","doi":"10.1016/j.immuni.2017.07.011","title":"Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition","year":2017,"lang":"en","type":"article","venue":"Immunity","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"H2020 European Research Council; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; European Crohn's and Colitis Organisation","keywords":"Biology; Gut flora; Inflammasome; Dysbiosis; Innate immune system; Immunity; Microbiology; Host (biology); Immunology; Immune system; Commensalism; Inflammation; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004530432,0.0003590387,0.000552361,0.0002717771,0.0001774745,0.001086973,0.0002808938,0.000735439,0.002238669],"category_scores_gemma":[0.0006898936,0.0002483028,0.0004758761,0.0002361653,0.0005486066,0.001009385,0.0007171766,0.0009127271,0.001089118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002907773,"about_ca_system_score_gemma":0.0002431348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001371294,"about_ca_topic_score_gemma":0.0002296164,"domain_scores_codex":[0.9993555,0.0001154512,0.00006147708,0.0001629976,0.0001770095,0.0001275516],"domain_scores_gemma":[0.9992074,0.00004170053,0.0002865384,0.0001420943,0.00008252879,0.0002396349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001450812,0.00003108985,0.00390163,0.0001010245,0.00002448231,0.00009653225,0.00004092354,0.00006108196,0.9894915,0.0003523024,0.0001903769,0.00425811],"study_design_scores_gemma":[0.000279127,0.001179067,0.250222,0.0001011512,0.0001603989,0.003835739,0.0007205614,0.002925312,0.7247389,0.00322998,0.01254382,0.0000638221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987028,0.003915032,0.004121617,0.0006498332,0.0001972681,0.00002081541,0.00107619,0.0001579418,0.002833377],"genre_scores_gemma":[0.9944584,0.0007773504,0.00215489,0.0002284593,0.00004372019,0.00001534151,0.0005248842,0.0000534772,0.001743406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002238669,"threshold_uncertainty_score":0.007489085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01707181888248027,"score_gpt":0.2847860334624712,"score_spread":0.267714214579991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}