{"id":"W2742583861","doi":"10.1007/s12010-017-2573-6","title":"Heterologous Expression of Aldehyde Dehydrogenase in Lactococcus lactis for Acetaldehyde Detoxification at Low pH","year":2017,"lang":"en","type":"article","venue":"Applied Biochemistry and Biotechnology","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Lactococcus lactis; Acetaldehyde; Nisin; Biochemistry; Aldehyde dehydrogenase; Chemistry; Heterologous expression; Yeast; Propionaldehyde; Recombinant DNA; Enzyme; Bacteria; Biology; Organic chemistry; Gene; Ethanol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001348364,0.0001497301,0.0003158588,0.00007718163,0.0001750815,0.000007463448,0.00014778,0.0006998159,0.00001621363],"category_scores_gemma":[0.0001282268,0.000132748,0.0000461144,0.00004350516,0.0003699601,0.0000225797,0.0001247975,0.0002158828,0.000004799714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005748805,"about_ca_system_score_gemma":0.00003731276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001042355,"about_ca_topic_score_gemma":0.00001807474,"domain_scores_codex":[0.9990444,0.000007469819,0.0002551631,0.0003689511,0.00007249588,0.0002515416],"domain_scores_gemma":[0.9989894,0.00005324453,0.0002634654,0.0005787529,0.00002641523,0.00008869464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006878474,0.0001355475,0.003044085,0.0005651292,0.00001147165,0.000006617524,0.00002567611,2.069119e-7,0.9887795,0.00009624361,0.00009970926,0.006548009],"study_design_scores_gemma":[0.002356996,0.0001176122,0.007372762,0.00009160125,0.00002552066,0.0000474576,0.0000405279,0.00005843131,0.9889234,0.00009762889,0.000755668,0.0001124019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968029,0.0002186472,0.00007620177,0.001887742,0.00003018318,0.0007531422,0.00002785866,0.00005959326,0.0001437408],"genre_scores_gemma":[0.9984613,0.000244501,0.0007057295,0.0002221857,0.00003514693,0.0001594712,0.00007788324,0.00001282303,0.00008092949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006435608,"threshold_uncertainty_score":0.5413305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03496870957329803,"score_gpt":0.3304203375159724,"score_spread":0.2954516279426744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}