{"id":"W2742743598","doi":"10.3390/children4080068","title":"Key Challenges in the Search for Innovative Drug Treatments for Special Populations. Converging Needs in Neonatology, Pediatrics, and Medical Genetics","year":2017,"lang":"en","type":"article","venue":"Children","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Pharmacy; Medicine; Action (physics); Neonatology; Key (lock); Intensive care medicine; Medical education; Family medicine; Computer science; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04292117,0.00065142,0.001567439,0.002354705,0.003077458,0.007977991,0.002391276,0.007267307,0.0155943],"category_scores_gemma":[0.04949699,0.0005175893,0.0008963417,0.002068222,0.007568604,0.01081023,0.009247383,0.01547671,0.003413142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004363768,"about_ca_system_score_gemma":0.02254871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00263137,"about_ca_topic_score_gemma":0.005892954,"domain_scores_codex":[0.9854235,0.008294648,0.00147682,0.00119282,0.002820697,0.0007914078],"domain_scores_gemma":[0.9022872,0.06051634,0.005547179,0.004199608,0.01132002,0.0161296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003039842,0.0007471824,0.008360787,0.006216451,0.0002128425,0.002372143,0.004447715,0.0008661266,0.00178021,0.1365995,0.1966516,0.6414414],"study_design_scores_gemma":[0.000142625,0.0004313395,0.006614486,0.008778989,0.000123755,0.003680719,0.01073888,0.0006294398,0.0006675751,0.2007357,0.7673137,0.0001427827],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.002409437,0.1165825,0.003390611,0.868862,0.001885508,0.00004855163,0.0001239811,0.0000563248,0.006641176],"genre_scores_gemma":[0.1170702,0.4843409,0.08888093,0.2793897,0.02133803,0.0006243748,0.0005659071,0.0001642948,0.007625705],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.04292117,"threshold_uncertainty_score":0.2269915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1637552563179497,"score_gpt":0.4341795202796502,"score_spread":0.2704242639617005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}