{"id":"W2742784867","doi":"10.1097/sla.0000000000002356","title":"Results of the First Prospective Multi-institutional Treatment Study in Children With Bilateral Wilms Tumor (AREN0534)","year":2017,"lang":"en","type":"article","venue":"Annals of Surgery","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; University of Alberta Hospital; Alberta Children's Hospital","funders":"National Cancer Institute","keywords":"Medicine; Nephrectomy; Wilms' tumor; Chemotherapy; Surgery; Vincristine; Induction chemotherapy; Kidney disease; Radiation therapy; Prospective cohort study; Kidney; Internal medicine; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001357207,0.0001070079,0.000183551,0.00003152701,0.0001171409,0.000008588988,0.0001369917,0.00004368873,0.000001153017],"category_scores_gemma":[0.00004619102,0.00005452009,0.0001055346,0.00004460949,0.0002143603,0.00000628815,0.00005072107,0.00004431524,4.780255e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001007059,"about_ca_system_score_gemma":0.0001422205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001087304,"about_ca_topic_score_gemma":0.0005854223,"domain_scores_codex":[0.9993404,0.00002278544,0.0002103478,0.0001966427,0.0001056905,0.000124099],"domain_scores_gemma":[0.9993154,0.000008789988,0.0002299953,0.0003461266,0.00007516603,0.0000245635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005654375,0.0004758953,0.9962593,0.000005193813,0.0002496266,0.000005931558,0.00008816372,0.0003089597,0.001416842,0.000002564565,0.0001620429,0.0004600514],"study_design_scores_gemma":[0.001024867,0.0002750899,0.8951526,0.00006694683,0.00001188465,0.000008153887,0.00002232486,0.000004393349,0.1032086,0.000004090343,0.0001518823,0.00006923737],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989321,0.0001985771,7.741405e-7,0.0002521816,0.00006739565,0.0002995212,0.00006862341,0.000001788434,0.0001790991],"genre_scores_gemma":[0.9995584,0.0001789789,0.000008365361,0.00003435381,0.00003907901,0.00002274019,0.00001562727,0.000005762231,0.0001367089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1017917,"threshold_uncertainty_score":0.2223265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06704328703762294,"score_gpt":0.3038098382381473,"score_spread":0.2367665512005243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}