{"id":"W2742784867","doi":"10.1097/sla.0000000000002356","title":"Results of the First Prospective Multi-institutional Treatment Study in Children With Bilateral Wilms Tumor (AREN0534)","year":2017,"lang":"en","type":"article","venue":"Annals of Surgery","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; University of Alberta Hospital; Alberta Children's Hospital","funders":"National Cancer Institute","keywords":"Medicine; Nephrectomy; Wilms' tumor; Chemotherapy; Surgery; Vincristine; Induction chemotherapy; Kidney disease; Radiation therapy; Prospective cohort study; Kidney; Internal medicine; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001527603,0.0003225026,0.0003826585,0.0006583451,0.000429796,0.0003928794,0.0002920155,0.0003405529,0.001588066],"category_scores_gemma":[0.002606506,0.0002128786,0.0004822426,0.0007957431,0.0003119561,0.0003472898,0.0003750206,0.0003958196,0.0002131575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006617305,"about_ca_system_score_gemma":0.0006408488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002957447,"about_ca_topic_score_gemma":0.005118173,"domain_scores_codex":[0.9988128,0.0005714321,0.0000918459,0.0001718237,0.0002321301,0.0001199683],"domain_scores_gemma":[0.9974869,0.0005608528,0.001124537,0.0001907813,0.0002340791,0.0004027446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001010819,0.0001793112,0.9951673,0.00001903802,0.0001128288,0.0001867046,0.00008099854,0.00008596919,0.0003044256,0.00002202565,0.0003736551,0.002456921],"study_design_scores_gemma":[0.0002250231,0.0008701411,0.997066,0.00001153807,0.00007493288,0.0006133051,0.00008321324,0.00007810207,0.0001529262,0.00001436559,0.0008044466,0.000006061422],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978893,0.0002109097,0.00008226201,0.00005739025,0.000004530434,0.00004591448,0.001161539,0.000004978627,0.0005432113],"genre_scores_gemma":[0.9965488,0.0001142756,0.000233369,0.00006305578,0.00001050395,0.0001033474,0.002680372,0.000005415664,0.0002408944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002957447,"threshold_uncertainty_score":0.008078873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06704328703762294,"score_gpt":0.3038098382381473,"score_spread":0.2367665512005243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}