{"id":"W2742949441","doi":"10.3389/fendo.2017.00162","title":"Enhanced Mortality to Metastatic Bladder Cancer Cell Line MB49 in Vasoactive Intestinal Peptide Gene Knockout Mice","year":2017,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Macrophage Migration Inhibitory Factor","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Institut national de la recherche scientifique","keywords":"Vasoactive intestinal peptide; Knockout mouse; Bladder cancer; Cancer; Gene knockout; Medicine; Cancer research; Endocrinology; Internal medicine; Chemistry; Gene; Receptor; Neuropeptide; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001616498,0.0003387284,0.0006575148,0.0002701632,0.0002044409,0.00002586868,0.0006691248,0.0001713868,0.0008923125],"category_scores_gemma":[0.0002676808,0.0003472119,0.00009383634,0.0001111912,0.0004652557,0.0002221599,0.0002697521,0.0006076996,0.0002184711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003633088,"about_ca_system_score_gemma":0.0001584819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005249912,"about_ca_topic_score_gemma":0.01143387,"domain_scores_codex":[0.9974416,0.0003542771,0.0005835373,0.0007118993,0.00005604445,0.0008526623],"domain_scores_gemma":[0.9986893,0.0001062588,0.0003219133,0.000717691,0.0001081286,0.00005674406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006370384,0.0005141668,0.09491039,0.00005131084,0.0005123838,0.0002448061,0.003694113,0.0004102728,0.8805461,0.000112108,0.01220607,0.006161261],"study_design_scores_gemma":[0.00308437,0.0002437715,0.1013119,0.00004086294,0.0001032908,0.00003720964,0.001457918,0.00004464251,0.8883294,0.0002213406,0.004676238,0.0004490517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981651,0.002527378,0.008619882,0.0003359235,0.004170112,0.0006358381,0.0001218732,0.00005191506,0.001886074],"genre_scores_gemma":[0.9901116,0.0002106024,0.004299555,0.000311537,0.00008115017,0.0003292859,0.00004992747,0.00003100863,0.004575347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008460583,"threshold_uncertainty_score":0.999898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0265189704335278,"score_gpt":0.3043719004308307,"score_spread":0.2778529299973029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}