{"id":"W2743141745","doi":"10.1039/c7tb01833a","title":"Biomaterials for polynucleotide delivery to anchorage-independent cells","year":2017,"lang":"en","type":"article","venue":"Journal of Materials Chemistry B","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto Public Health; Alberta Hospital Edmonton; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Polynucleotide; Transfection; Endocytosis; Nucleic acid; Biomaterial; Cell; Nanotechnology; Materials science; Cell biology; Chemistry; Biophysics; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004855577,0.000190829,0.0003378231,0.00002807646,0.0001585917,0.0002855524,0.0007505522,0.0001698649,0.0001816498],"category_scores_gemma":[0.0001800095,0.0001695669,0.0001654778,0.00001152288,0.00004767095,0.00001754066,0.0002003816,0.00003109045,0.0000218567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002193806,"about_ca_system_score_gemma":0.00009434113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001337422,"about_ca_topic_score_gemma":0.00000233002,"domain_scores_codex":[0.998775,0.00002412767,0.0005421347,0.0002348344,0.0001611589,0.0002627479],"domain_scores_gemma":[0.9982924,0.000009136379,0.0006892721,0.0005319628,0.000311314,0.0001658536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007338449,0.00004565581,0.00005579182,0.00006952686,0.00009145742,0.00001941342,0.00001577954,0.00001036244,0.9868357,9.524567e-7,0.01182341,0.0002980897],"study_design_scores_gemma":[0.0006599355,0.0002796307,0.0005314267,0.00007155939,0.00003895658,0.00007966956,0.00003823672,4.002112e-7,0.9840103,0.00003027282,0.01406459,0.0001950151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975686,0.00009318974,0.000266141,0.000226864,0.001298928,0.0001451667,0.0001794822,0.000004048879,0.0002175485],"genre_scores_gemma":[0.9957928,0.0001262328,0.001134936,0.0001766897,0.001871838,0.00001015325,0.00002124242,0.00002777488,0.0008383501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002825409,"threshold_uncertainty_score":0.691474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01459812431900355,"score_gpt":0.271356729507519,"score_spread":0.2567586051885155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}