{"id":"W2743373469","doi":"10.1186/s13195-017-0283-5","title":"On the path to 2025: understanding the Alzheimer’s disease continuum","year":2017,"lang":"en","type":"review","venue":"Alzheimer s Research & Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":557,"is_retracted":false,"has_abstract":true,"ca_institutions":"Eli Lilly (Canada)","funders":"National Institute on Aging","keywords":"Disease; Medicine; Biomarker; Natural history; Asymptomatic; Intensive care medicine; Neuroscience; Psychology; Pathology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001557441,0.000943248,0.00132737,0.002593339,0.0006769678,0.002524906,0.001157246,0.002474318,0.004623872],"category_scores_gemma":[0.002168107,0.0002841154,0.0007659449,0.002448523,0.001470794,0.006249652,0.001620798,0.005255355,0.00288849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00171258,"about_ca_system_score_gemma":0.00426324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0025432,"about_ca_topic_score_gemma":0.00381041,"domain_scores_codex":[0.9994507,0.0001659323,0.00007922018,0.00005717084,0.0001990353,0.00004786945],"domain_scores_gemma":[0.9990421,0.0004612383,0.000092738,0.00002663501,0.0002835445,0.00009369605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007902881,0.00005395889,0.0002581209,0.01997347,0.0001032934,0.0002648367,0.0006013259,0.0002911785,0.000706182,0.0401778,0.09776594,0.8397249],"study_design_scores_gemma":[0.000006616765,0.00002976936,0.0004136392,0.009068679,0.00004320297,0.0006868642,0.0003487838,0.00004967811,0.00008156519,0.01365046,0.9756056,0.00001510127],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007994506,0.993246,0.0001740737,0.003827305,0.001053756,0.00000461702,0.0000135687,0.000009339436,0.001591444],"genre_scores_gemma":[0.0007498036,0.9952672,0.0003871268,0.002043777,0.0006556108,0.000007942632,0.00002886223,0.000003936421,0.0008558531],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004623872,"threshold_uncertainty_score":0.01546836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5521856821984469,"score_gpt":0.5162792480049575,"score_spread":0.03590643419348938,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}