{"id":"W2743948277","doi":"10.1016/j.vaccine.2017.07.070","title":"Vaccination with Shigella flexneri 2a conjugate induces type 2a and cross-reactive type 6 antibodies in humans but not in mice","year":2017,"lang":"en","type":"article","venue":"Vaccine","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Fogarty International Center; National Institutes of Health","keywords":"Shigella flexneri; Microbiology; Shigellosis; Antibody; Conjugate vaccine; Conjugate; Medicine; Biology; Virology; Shigella; Immunology; Escherichia coli; Immunization; Bacteria; Salmonella","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003525381,0.0005737006,0.0002785292,0.0002697822,0.0001214411,0.0002530825,0.0001282332,0.0005925304,0.001887178],"category_scores_gemma":[0.0002525453,0.0003014728,0.0003507135,0.00007300957,0.0002366752,0.0002432106,0.000146329,0.0008338455,0.0005239804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001785849,"about_ca_system_score_gemma":0.0001168385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003033549,"about_ca_topic_score_gemma":0.0002246281,"domain_scores_codex":[0.9997925,0.0000585608,0.00001074305,0.00006540785,0.00002787189,0.00004489443],"domain_scores_gemma":[0.9998856,0.00002358734,0.00002977604,0.00002450072,0.00001183106,0.0000247641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001128287,0.0004162111,0.001791961,0.00005536794,0.00004509025,0.0002245325,0.00005115363,0.00008589052,0.9907336,0.0001705846,0.0003577142,0.004939531],"study_design_scores_gemma":[0.0004917472,0.01927963,0.06163026,0.00003462378,0.0001773445,0.00453415,0.0001177334,0.001346392,0.9034762,0.0003312771,0.008563653,0.00001689512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960943,0.0007575955,0.001541262,0.0001276264,0.0000799336,0.00003383653,0.0001017821,0.00007181702,0.001191833],"genre_scores_gemma":[0.9970564,0.0003658139,0.0003168021,0.0001584102,0.00002888344,0.00001479035,0.0002051099,0.00001602106,0.001837833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001887178,"threshold_uncertainty_score":0.006313205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02428396191668555,"score_gpt":0.3371795578913098,"score_spread":0.3128955959746243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}