{"id":"W2744013535","doi":"10.1055/s-0036-1588515","title":"Chemoenzymatic Formal Total Synthesis of Pancratistatin from Narciclasine-Type Compounds via Myers Transposition: Model Study for a Short Conversion of Narciclasine to Pancratistatin","year":2017,"lang":"en","type":"article","venue":"Synlett","topic":"Chemical synthesis and alkaloids","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Chemistry; Dihydroxylation; Transposition (logic); Combinatorial chemistry; Enantioselective synthesis; Allylic rearrangement; Stereochemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000223726,0.0003414845,0.0008465569,0.00005201589,0.0002884443,0.0000565583,0.0005252272,0.0001471773,0.0002959759],"category_scores_gemma":[0.0003471339,0.0003286081,0.0001852306,0.0001110005,0.0001872217,0.0002526284,0.0001027119,0.0001477273,0.000006316114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008434342,"about_ca_system_score_gemma":0.0000812319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002663281,"about_ca_topic_score_gemma":0.00004094811,"domain_scores_codex":[0.9978017,0.00002679622,0.0008300643,0.0004676177,0.0004754585,0.0003983851],"domain_scores_gemma":[0.997816,0.0005136624,0.0003624009,0.0008184639,0.0003126637,0.0001768477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001060511,0.0006503956,0.003720903,0.0006796171,0.0002125944,0.00000692585,0.0009988823,0.00009462378,0.9865401,0.00003094643,0.0007688734,0.005235667],"study_design_scores_gemma":[0.001260723,0.0002475762,0.003369932,0.0003661736,0.0002966954,0.000004228701,0.0007177233,0.02793827,0.9651541,0.0001975789,0.0000530721,0.0003939899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899992,0.00003262775,0.0070807,0.0003838171,0.00007009837,0.0004851608,0.001201528,0.00004011725,0.0007067861],"genre_scores_gemma":[0.988333,0.000005076266,0.0110245,0.00004824037,0.00009369007,0.0001199422,0.0001339024,0.00005225199,0.0001893745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02784364,"threshold_uncertainty_score":0.9999166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02024319541286037,"score_gpt":0.2695754874169468,"score_spread":0.2493322920040864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}