{"id":"W2744142295","doi":"10.1016/j.clim.2017.08.002","title":"Retinoic acid induction of CD1d expression primes chronic lymphocytic leukemia B cells for killing by CD8+ invariant natural killer T cells","year":2017,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Trinity College","funders":"Irish Research Council","keywords":"CD1D; Natural killer T cell; Degranulation; Cytotoxic T cell; Chronic lymphocytic leukemia; Immunology; CD8; Cancer research; Biology; Antigen; Leukemia; Cell biology; In vitro; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000734178,0.0003352759,0.0007819375,0.0001262101,0.0006943801,0.0000434246,0.0007030102,0.001157468,0.0007760451],"category_scores_gemma":[0.0006282566,0.0002924484,0.0004202249,0.00005594304,0.00100948,0.0003555228,0.0003022883,0.0009828729,0.0005678046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007711838,"about_ca_system_score_gemma":0.000597198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001756945,"about_ca_topic_score_gemma":0.000006669979,"domain_scores_codex":[0.996971,0.0004537987,0.001290368,0.0006664722,0.00005314259,0.0005652136],"domain_scores_gemma":[0.9966793,0.0006291535,0.001318001,0.001082425,0.0002575557,0.00003353839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001278329,0.0001012141,0.00006536725,0.00003449021,0.0003175343,0.000001150856,0.00008055291,0.000009984314,0.9425848,0.0000737436,0.04869019,0.006762695],"study_design_scores_gemma":[0.004156222,0.0009418642,0.0006989145,0.000132481,0.0001034937,0.00002619292,0.0001215193,0.0001535081,0.8664189,0.0000597365,0.1269121,0.0002751053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9101124,0.00939953,0.001335013,0.0002499342,0.07732963,0.0008035019,0.00001342842,0.0001367727,0.0006197339],"genre_scores_gemma":[0.9734683,0.001773292,0.0002341007,0.0001787337,0.000240655,0.00005720277,0.0002429541,0.00004442735,0.02376035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07822189,"threshold_uncertainty_score":0.9999528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02679105058451135,"score_gpt":0.3052606113902043,"score_spread":0.2784695608056929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}