{"id":"W2744282918","doi":"10.1007/978-1-4939-7219-7_4","title":"Targeting HER2 in Advanced Breast Cancer","year":2017,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Metastatic breast cancer; Oncology; Breast cancer; Internal medicine; Human Epidermal Growth Factor Receptor 2; Clinical trial; Cancer; Targeted therapy; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000793085,0.001288689,0.00182669,0.002202155,0.0002101873,0.001046501,0.0008836376,0.001078493,0.004270369],"category_scores_gemma":[0.0009438472,0.0004065423,0.0005185429,0.00150221,0.0004842041,0.001641182,0.0009585,0.00260185,0.002169631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006089236,"about_ca_system_score_gemma":0.001055188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006464777,"about_ca_topic_score_gemma":0.001849017,"domain_scores_codex":[0.9998097,0.00003229442,0.00002654001,0.00002880632,0.00007565867,0.00002702106],"domain_scores_gemma":[0.999719,0.0001239441,0.00004537284,0.000009077208,0.00006940334,0.0000331839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001164769,0.00009966741,0.00008010044,0.01863584,0.0001121134,0.0001264879,0.00003376266,0.000349205,0.002025886,0.002812178,0.04599962,0.9296088],"study_design_scores_gemma":[0.0000873161,0.0001364174,0.0004056781,0.004113616,0.0002635861,0.0006985705,0.0000320097,0.0001696042,0.000907039,0.002267405,0.9908944,0.00002435954],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000835073,0.99828,0.0002010704,0.0002676564,0.0003020942,0.000009597868,0.00002171608,0.00001021258,0.0008240535],"genre_scores_gemma":[0.0005709131,0.997839,0.0002405944,0.0003376762,0.0002118643,0.00001139518,0.0000371398,0.000002254507,0.0007491568],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004270369,"threshold_uncertainty_score":0.0142858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1860048241326859,"score_gpt":0.6291759151960609,"score_spread":0.4431710910633749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}