{"id":"W2744341617","doi":"10.1097/j.pain.0000000000001027","title":"Age-dependent plasticity in endocannabinoid modulation of pain processing through postnatal development","year":2017,"lang":"en","type":"article","venue":"Pain","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Endocannabinoid system; Rostral ventromedial medulla; Neuroscience; Brainstem; Cannabinoid receptor; Periaqueductal gray; Nociception; Medicine; Palmitoylethanolamide; Hyperalgesia; DAMGO; Chronic pain; Noxious stimulus; Receptor; Biology; Opioid; Endocrinology; Central nervous system; Internal medicine; Opioid receptor; Antagonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003083999,0.0001449624,0.0002922,0.0001182448,0.0002031754,0.00006222288,0.0001915555,0.00008761573,0.0000657287],"category_scores_gemma":[0.002470712,0.0001287049,0.00005485693,0.00009039153,0.000135668,0.0001632915,0.0001084591,0.000235414,0.000006258995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002035318,"about_ca_system_score_gemma":0.0004348624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005826827,"about_ca_topic_score_gemma":0.000407775,"domain_scores_codex":[0.9981434,0.0002638288,0.0003844105,0.0002886359,0.0005631971,0.0003564728],"domain_scores_gemma":[0.9992435,0.00003788547,0.0001728494,0.0002939168,0.0001497199,0.0001021217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0007986469,0.001014647,0.1524915,0.002159107,0.00007356986,0.001007668,0.006707024,0.0002922246,0.1007169,0.0003044723,0.006917156,0.727517],"study_design_scores_gemma":[0.00246029,0.0003025409,0.9150648,0.0006465483,0.00001637306,0.00003147486,0.000685833,0.0196585,0.05090992,0.0002608231,0.009654302,0.0003085651],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9769694,0.0001686399,0.01676144,0.003084264,0.00006125272,0.0006279976,0.000006764963,0.00003412408,0.002286113],"genre_scores_gemma":[0.9963359,0.00000863073,0.001283447,0.0001621587,0.00007786564,0.00006424262,0.00002115884,0.0000214359,0.0020252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7625733,"threshold_uncertainty_score":0.5248433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03078260705833764,"score_gpt":0.3162305222691908,"score_spread":0.2854479152108532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}