{"id":"W2744425972","doi":"10.1136/bcr-2017-220974","title":"Atypical haemolytic uremic syndrome (aHUS) and membranoproliferative glomerulonephritis (MPGN), different diseases or a spectrum of complement-mediated glomerular diseases?","year":2017,"lang":"en","type":"article","venue":"BMJ Case Reports","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; London Health Sciences Centre","funders":"","keywords":"Atypical hemolytic uremic syndrome; Membranoproliferative glomerulonephritis; Thrombotic microangiopathy; Eculizumab; Medicine; Glomerulopathy; Alternative complement pathway; Immunology; Proteinuria; Glomerulonephritis; Renal biopsy; Nephrology; Complement system; Internal medicine; Pathology; Kidney; Antibody; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002295993,0.0005432954,0.001263076,0.0002017431,0.0008218405,0.0001135407,0.0002424636,0.0001802891,0.002800111],"category_scores_gemma":[0.00100996,0.0004351444,0.0002867783,0.0001006525,0.0008407181,0.0002416844,0.0005863529,0.000216979,0.00005295029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001179402,"about_ca_system_score_gemma":0.0002387891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004475192,"about_ca_topic_score_gemma":0.0004183965,"domain_scores_codex":[0.9964147,0.0003534249,0.001377733,0.0009041105,0.0002337436,0.0007163228],"domain_scores_gemma":[0.9962226,0.0003819722,0.001327467,0.001668633,0.0001231917,0.0002761829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002277357,0.00157485,0.5118192,0.001341599,0.002469244,0.4663888,0.0002687811,0.000002911603,0.007580219,0.0003857086,0.004651667,0.001239617],"study_design_scores_gemma":[0.00424717,0.0006112129,0.5480243,0.0009753609,0.001135337,0.439406,0.0003787605,0.0000382059,0.002343988,0.0005954037,0.001433308,0.0008109755],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890762,0.005386078,0.00003360444,0.0003902232,0.0007473398,0.002424633,0.001741957,0.0001322386,0.00006770033],"genre_scores_gemma":[0.998266,0.0001013441,0.0000175712,0.00006143993,0.00007163724,0.000354605,0.0007720502,0.00004899995,0.0003063768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03620504,"threshold_uncertainty_score":0.99981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02502347402223238,"score_gpt":0.303061475197992,"score_spread":0.2780380011757596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}