{"id":"W2744690554","doi":"10.1101/cshperspect.a031666","title":"Regulation of Energy Metabolism by Bone-Derived Hormones","year":2017,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Medicine","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Endocrinology; Internal medicine; Hypothalamus; Osteocalcin; Bone remodeling; Hormone; Chemistry; Receptor; Secretion; Appetite; Lipid metabolism; Biology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004556554,0.0004241375,0.002000579,0.0005324186,0.0001593342,0.00002991173,0.0006468141,0.0002655291,0.00007540063],"category_scores_gemma":[0.001309151,0.0003513783,0.0002468585,0.0003719915,0.0007046571,0.0002157999,0.000145424,0.0003312704,0.000007715909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001699244,"about_ca_system_score_gemma":0.00011958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001524965,"about_ca_topic_score_gemma":0.000006218584,"domain_scores_codex":[0.9972966,0.00027638,0.0007777424,0.0008009091,0.0005449921,0.000303378],"domain_scores_gemma":[0.9975016,0.0003223418,0.001032701,0.0009418567,0.00009566662,0.0001058428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001012549,0.0005592706,0.0000294757,0.007031132,0.0001633895,0.0000981241,0.001430436,0.00001061886,0.3557918,0.4801746,0.001610537,0.1529993],"study_design_scores_gemma":[0.0005772012,0.0000590488,0.001879777,0.006721961,0.0002136825,0.00000262188,0.00004378642,0.00003120103,0.01060802,0.0001403993,0.9793544,0.000367888],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008097579,0.9962779,0.0001656656,0.0001760739,0.0003610083,0.0004059588,0.00001498334,0.00005618675,0.001732412],"genre_scores_gemma":[0.03736937,0.9614709,0.00009023047,0.00002565011,0.0004086435,0.00004578962,0.000002574106,0.000055386,0.000531443],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9777439,"threshold_uncertainty_score":0.9998938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0684723029718749,"score_gpt":0.3401059747534784,"score_spread":0.2716336717816035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}