{"id":"W2744741840","doi":"10.1111/apa.14008","title":"Therapeutic drug monitoring was helpful in guiding the decision‐making process for children receiving infliximab for inflammatory bowel disease","year":2017,"lang":"en","type":"article","venue":"Acta Paediatrica","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; University of Alberta; University of Manitoba","funders":"University of Manitoba","keywords":"Medicine; Infliximab; Inflammatory bowel disease; Disease; Drug; Intensive care medicine; Therapeutic drug monitoring; Inflammatory Bowel Diseases; Internal medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003726039,0.0002805256,0.0002811634,0.0008708996,0.000798146,0.001358645,0.0004496756,0.0005739521,0.001541224],"category_scores_gemma":[0.02971369,0.0001947717,0.00038749,0.0009101449,0.0007421513,0.000954729,0.0006622596,0.00129766,0.0001829558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001885015,"about_ca_system_score_gemma":0.004433128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02327219,"about_ca_topic_score_gemma":0.0348663,"domain_scores_codex":[0.9955608,0.002008152,0.0005904339,0.0003525458,0.001030315,0.0004578358],"domain_scores_gemma":[0.9790148,0.009488881,0.008311333,0.0004954728,0.001714421,0.0009751091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001222357,0.00002712083,0.9683601,0.00008810578,0.00003424094,0.0004480259,0.0006930899,0.0002253515,0.0001866954,0.0001094714,0.0007693056,0.02893624],"study_design_scores_gemma":[0.00002935408,0.0003108848,0.9796021,0.0008011769,0.0001835094,0.004840866,0.003339597,0.002084844,0.001391466,0.0002667933,0.007112412,0.00003694045],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850258,0.005188028,0.0009303823,0.003788515,0.00008411898,0.00006394639,0.0004067249,0.00004934341,0.004463137],"genre_scores_gemma":[0.996635,0.0007965505,0.002124289,0.0002372147,0.00003542789,0.000007204508,0.0000764508,0.000004670088,0.00008324719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02327219,"threshold_uncertainty_score":0.04627347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01604354978979668,"score_gpt":0.2942979408649233,"score_spread":0.2782543910751266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}