{"id":"W2744776760","doi":"10.1016/j.jaad.2017.06.042","title":"When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council","year":2017,"lang":"en","type":"review","venue":"Journal of the American Academy of Dermatology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":236,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Sanofi Genzyme; Novartis Pharma; LEO Pharma; LEO Fondet; Astellas Pharma; Yonsei University; Dermira; Chugai Pharmaceutical; Wellcome Trust; Regeneron Pharmaceuticals; Genentech; Valeant Pharmaceuticals International; Sanofi; Biotechnology and Biological Sciences Research Council; Amgen; Pfizer; Les Laboratories Pierre Fabre; Medical Research Council; Celgene; Galderma; AstraZeneca; Eli Lilly and Company; GlaxoSmithKline","keywords":"Medicine; Atopic dermatitis; Warrant; Dermatology; Systemic therapy; Intensive care medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0306262,0.001597694,0.004119881,0.008709762,0.001391998,0.002756928,0.005206947,0.005123034,0.004531616],"category_scores_gemma":[0.0722063,0.001007107,0.004789586,0.005884792,0.00115954,0.005103192,0.002333749,0.004187788,0.002159358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003782528,"about_ca_system_score_gemma":0.01783162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009992227,"about_ca_topic_score_gemma":0.02037093,"domain_scores_codex":[0.9812383,0.006438816,0.007802592,0.000807051,0.003253808,0.0004595251],"domain_scores_gemma":[0.9527543,0.01931721,0.00592994,0.0007879766,0.01976926,0.00144129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000220394,0.00007636308,0.002600335,0.1378779,0.001082997,0.0007150504,0.001397715,0.0003090936,0.0005450766,0.001931943,0.2356245,0.6176187],"study_design_scores_gemma":[0.0003242406,0.0001189929,0.004370741,0.4521953,0.004531156,0.001383105,0.001918044,0.0002999916,0.00037245,0.00441051,0.529918,0.0001573841],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000864599,0.8997889,0.002309378,0.08418705,0.004928562,0.001368931,0.0008903234,0.00006986954,0.005592457],"genre_scores_gemma":[0.01252837,0.9360999,0.02118901,0.02379825,0.001581531,0.001712949,0.001366508,0.00003739219,0.001686008],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0306262,"threshold_uncertainty_score":0.1619688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1426474843587881,"score_gpt":0.3945985854500205,"score_spread":0.2519511010912324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}