{"id":"W2744882033","doi":"10.21873/anticanres.11797","title":"Cell Cycle Arrest and Apoptosis Induced by Kinamycin F in Human Osteosarcoma Cells","year":2017,"lang":"en","type":"article","venue":"Anticancer Research","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Associazione Italiana per la Ricerca sul Cancro; Fondazione del Monte di Bologna e Ravenna; University of Waterloo","keywords":"Cell cycle; Cell growth; Apoptosis; Osteosarcoma; Flow cytometry; Cyclin D1; Cell culture; Cell cycle checkpoint; Cell; Biology; Population; Viability assay; Programmed cell death; Cancer research; Cyclin; Molecular biology; Cell biology; Medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008081473,0.0001271829,0.000271368,0.0001566165,0.0004768652,0.0001558923,0.0002895498,0.0001212945,0.0001714922],"category_scores_gemma":[0.0001742106,0.000100514,0.00003497407,0.0001504422,0.0003413701,0.0001244974,0.0002494177,0.0006134735,0.00004625666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007356774,"about_ca_system_score_gemma":0.0000721356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005022171,"about_ca_topic_score_gemma":0.0001967435,"domain_scores_codex":[0.9983519,0.00009580125,0.0001892892,0.0004525471,0.0003811479,0.0005293359],"domain_scores_gemma":[0.9989347,0.00007809018,0.00005357138,0.0006540423,0.0001171679,0.0001623794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000883402,0.000145932,0.00393527,0.0001247835,0.00000930108,0.00001255386,0.0001005487,1.877457e-8,0.9821835,0.00004209484,0.007605985,0.005751634],"study_design_scores_gemma":[0.000911318,0.0002336162,0.02179874,0.0001516211,0.00001096466,0.000001576536,0.00009529114,0.00001286323,0.9733646,0.00007457059,0.003219888,0.0001249352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859949,0.0003829021,1.660896e-7,0.007798965,0.00009111506,0.0004535362,0.00001168709,0.00001270963,0.00525403],"genre_scores_gemma":[0.9976404,0.0003356375,0.00005751501,0.0001190491,0.0001830963,0.000004017531,0.00000526966,0.00002176205,0.001633293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01786347,"threshold_uncertainty_score":0.7592053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05773417674666839,"score_gpt":0.3802000619387826,"score_spread":0.3224658851921142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}