{"id":"W2744882033","doi":"10.21873/anticanres.11797","title":"Cell Cycle Arrest and Apoptosis Induced by Kinamycin F in Human Osteosarcoma Cells","year":2017,"lang":"en","type":"article","venue":"Anticancer Research","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Associazione Italiana per la Ricerca sul Cancro; Fondazione del Monte di Bologna e Ravenna; University of Waterloo","keywords":"Cell cycle; Cell growth; Apoptosis; Osteosarcoma; Flow cytometry; Cyclin D1; Cell culture; Cell cycle checkpoint; Cell; Biology; Population; Viability assay; Programmed cell death; Cancer research; Cyclin; Molecular biology; Cell biology; Medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008302126,0.0002389407,0.0001660128,0.0002117024,0.0001384066,0.000102542,0.0000652001,0.0001568972,0.001279803],"category_scores_gemma":[0.00008216256,0.0000582956,0.0001489207,0.000135356,0.0001115386,0.0001113743,0.0000962252,0.0001928546,0.0002400047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001781287,"about_ca_system_score_gemma":0.0001501969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007761021,"about_ca_topic_score_gemma":0.0008827107,"domain_scores_codex":[0.9999261,0.00001593296,0.00001026046,0.00001382251,0.0000195941,0.00001433486],"domain_scores_gemma":[0.9999552,0.00001118437,0.00001184776,0.000005542533,0.000009144614,0.000007109393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002778833,0.00003445539,0.0003843491,0.00006723213,0.000004631753,0.0001136813,0.00003181065,0.00008243755,0.9971161,0.00003513657,0.00004350489,0.001808739],"study_design_scores_gemma":[0.00003746513,0.0008824948,0.007484645,0.000006613486,0.00001323865,0.0005621582,0.00004375245,0.0003950847,0.9888151,0.00003690107,0.001718393,0.000004231287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936476,0.003101165,0.001431541,0.00005504088,0.00002300304,0.00003386995,0.0002765122,0.00003865827,0.001392526],"genre_scores_gemma":[0.995905,0.00115864,0.001184547,0.00002831288,0.000007308245,0.00004528271,0.0003788433,0.000003955703,0.001287966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001279803,"threshold_uncertainty_score":0.004281342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05773417674666839,"score_gpt":0.3802000619387826,"score_spread":0.3224658851921142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}