{"id":"W2745534693","doi":"10.1080/13880209.2017.1345952","title":"Caffeic acid methyl and ethyl esters exert potential antidiabetic effects on glucose and lipid metabolism in cultured murine insulin-sensitive cells through mechanisms implicating activation of AMPK","year":2017,"lang":"en","type":"article","venue":"Pharmaceutical Biology","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Université de Montréal; Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research","keywords":"AMPK; Caffeic acid; Chemistry; Metabolism; Insulin; Biochemistry; Carbohydrate metabolism; Lipid metabolism; Glucose uptake; Biology; Enzyme; Endocrinology; Antioxidant; Protein kinase A","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003145318,0.000270003,0.0004759807,0.00005559132,0.0001409608,0.00002804625,0.0001852033,0.000295784,0.000005694255],"category_scores_gemma":[0.0002158188,0.0002290653,0.00007282923,0.00005470701,0.0003378919,0.00001816734,0.0002406228,0.0002341152,0.000002007354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001119781,"about_ca_system_score_gemma":0.00002739972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004096698,"about_ca_topic_score_gemma":0.000004804551,"domain_scores_codex":[0.9983522,0.0002865081,0.000287778,0.000590681,0.00009223109,0.0003906054],"domain_scores_gemma":[0.9991643,0.00007612811,0.0002165388,0.0003442035,0.00007427583,0.0001245846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002634448,0.00006727785,0.0001203324,0.00007623158,0.00007875143,0.00000209298,0.0001093217,0.000002649755,0.912832,0.0004955661,0.000009173888,0.08594313],"study_design_scores_gemma":[0.002319425,0.000228473,0.003023016,0.00003480036,0.00009283606,0.000004117848,0.00004429985,0.00009684049,0.9896896,0.0007645324,0.003461731,0.0002403618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9781142,0.01930483,0.001470933,0.0001861455,0.0003865547,0.0004181086,0.00003869205,0.000009829662,0.0000706514],"genre_scores_gemma":[0.9716484,0.02564017,0.001380636,0.0009335166,0.0002630687,0.00004341318,0.00006437629,0.00002208911,0.000004321168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08570277,"threshold_uncertainty_score":0.9341013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01584088604021178,"score_gpt":0.315533267329053,"score_spread":0.2996923812888412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}