{"id":"W2745909886","doi":"10.1016/j.clml.2017.08.100","title":"High-dose Thiotepa, Busulfan, Cyclophosphamide, and Autologous Stem Cell Transplantation as Upfront Consolidation for Systemic Non-Hodgkin Lymphoma With Synchronous Central Nervous System Involvement","year":2017,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"CNS Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Sigma Theta Tau International; Otsuka Pharmaceutical; Roche; Merck; Pfizer","keywords":"ThioTEPA; Busulfan; Medicine; Cyclophosphamide; Transplantation; Lymphoma; Central nervous system; Consolidation (business); Autologous stem-cell transplantation; Hematopoietic stem cell transplantation; Chemotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003638177,0.0004017046,0.000608104,0.0005331311,0.0004489457,0.0004041429,0.0004655364,0.0002964058,0.001089993],"category_scores_gemma":[0.0004510981,0.0001540047,0.0004379424,0.0005172619,0.0003148639,0.0003777239,0.0003188186,0.0008811716,0.0002489974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005910574,"about_ca_system_score_gemma":0.0008572779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00120408,"about_ca_topic_score_gemma":0.006661393,"domain_scores_codex":[0.9998778,0.00003624523,0.00001355127,0.00001791209,0.00002157925,0.00003285852],"domain_scores_gemma":[0.9998106,0.00003530687,0.00002150216,0.00002300246,0.00001083455,0.00009882999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.03673914,0.01170714,0.1108351,0.0005697826,0.001022308,0.02567293,0.0006168032,0.007458868,0.040964,0.002087035,0.009483417,0.7528434],"study_design_scores_gemma":[0.02184249,0.1132023,0.6713959,0.0005407521,0.002212171,0.0840968,0.0006834216,0.02330455,0.03754411,0.00486144,0.04015358,0.0001625881],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988061,0.005628738,0.001029392,0.0004661121,0.0001714934,0.0001893804,0.0001221641,0.00009531257,0.004236458],"genre_scores_gemma":[0.9961451,0.00147641,0.001122885,0.0001607939,0.00009507421,0.00004909656,0.000226374,0.000009752928,0.0007144354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00120408,"threshold_uncertainty_score":0.004288435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0165036546270046,"score_gpt":0.2807450717922301,"score_spread":0.2642414171652255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}