{"id":"W2746285343","doi":"10.1371/journal.pmed.1002369","title":"Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials","year":2017,"lang":"en","type":"review","venue":"PLoS Medicine","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":180,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton; Queen's University; Impact","funders":"Canadian Institutes of Health Research; McMaster University","keywords":"Medicine; Pregabalin; Gabapentin; Meta-analysis; Randomized controlled trial; MEDLINE; Adverse effect; Confidence interval; Data extraction; Physical therapy; Chronic pain; Relative risk; Clinical trial; Grading (engineering); Systematic review; Internal medicine; Alternative medicine; Psychiatry; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01694072,0.003272438,0.02657665,0.008281413,0.0008132678,0.003645801,0.002692441,0.002443111,0.004756601],"category_scores_gemma":[0.04376115,0.001599819,0.03820603,0.008421507,0.0009789057,0.002226887,0.001785145,0.002204644,0.0003223698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003433505,"about_ca_system_score_gemma":0.004972278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004726541,"about_ca_topic_score_gemma":0.01010626,"domain_scores_codex":[0.9846848,0.006304867,0.005624649,0.001347167,0.001663376,0.000375171],"domain_scores_gemma":[0.9680023,0.02332017,0.00578854,0.0006531647,0.001926322,0.0003095648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002189594,0.00003046515,0.001583574,0.6139078,0.3697419,0.00008133824,0.00006115761,0.0003144312,0.0001311304,0.0001057805,0.0003804723,0.01147245],"study_design_scores_gemma":[0.001007297,0.0002501619,0.001936247,0.05316821,0.9416723,0.00008512006,0.00004147281,0.0001283916,0.00009635694,0.0001748497,0.001415015,0.00002454494],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002804608,0.9953358,0.0003812876,0.0001619649,0.0001128963,0.0005454475,0.0004341543,0.00001988157,0.0002039851],"genre_scores_gemma":[0.08545551,0.9077951,0.002282552,0.0008863879,0.0002682015,0.002302406,0.0007297677,0.00002810293,0.0002519191],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02657665,"threshold_uncertainty_score":0.0895921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2338055978128452,"score_gpt":0.4171280961768881,"score_spread":0.1833224983640429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}