{"id":"W2746319289","doi":"10.1161/circresaha.117.311541","title":"Allele-Specific Gene Silencing","year":2017,"lang":"en","type":"letter","venue":"Circulation Research","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Heart Institute","funders":"Canadian Institutes of Health Research","keywords":"Gene silencing; Allele; Gene; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001499528,0.0004982774,0.0005334556,0.0002319351,0.0006803818,0.001289945,0.0005977115,0.007011255,0.005415723],"category_scores_gemma":[0.004127773,0.0001881206,0.0007190018,0.0001879827,0.00100389,0.0005991414,0.0005865082,0.008316392,0.002517497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007711445,"about_ca_system_score_gemma":0.0006143973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004578574,"about_ca_topic_score_gemma":0.001030738,"domain_scores_codex":[0.9991843,0.0002368248,0.00006563341,0.0001223694,0.0002419655,0.0001489898],"domain_scores_gemma":[0.9988496,0.0007581376,0.00007233409,0.0001068531,0.00009200814,0.0001210744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004893337,0.0003701891,0.003532241,0.0002682713,0.0001801787,0.02511072,0.0004149,0.0006924937,0.06109248,0.05079164,0.6581228,0.1989348],"study_design_scores_gemma":[0.0004797655,0.0007369799,0.002155835,0.0001888687,0.0001833178,0.02240193,0.0002689337,0.002486052,0.03105708,0.02736983,0.912601,0.00007044793],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.02482049,0.01124373,0.01032137,0.8725316,0.03227681,0.000171697,0.0005244316,0.0007903015,0.04731962],"genre_scores_gemma":[0.2612267,0.0125597,0.006275472,0.6389312,0.02430984,0.0004053001,0.000859231,0.0002741242,0.05515843],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007011255,"threshold_uncertainty_score":0.01811743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1285000888563548,"score_gpt":0.3868771191401459,"score_spread":0.2583770302837911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}