{"id":"W2746335487","doi":"","title":"Insight into the biological activity of a naturally-derived dithiopyrrolone with a wide spectrum activity against metastatic cancer models","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Cancer; Medicine; Breast cancer; Trastuzumab; Metastatic breast cancer; Biodistribution; Metastasis; Cancer research; Melanoma; Pharmacology; Oncology; Internal medicine; In vivo; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007275733,0.0002066417,0.0003103478,0.00005499793,0.0003660171,0.0000357118,0.0005710287,0.0001379621,0.000321818],"category_scores_gemma":[0.0001294291,0.0001276183,0.0000859002,0.0006579618,0.0008532463,0.0001688092,0.000225985,0.001182366,0.000003616259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000377701,"about_ca_system_score_gemma":0.0003967923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002228017,"about_ca_topic_score_gemma":0.00283103,"domain_scores_codex":[0.9980108,0.00008553411,0.0002061915,0.0004980977,0.0006033714,0.000596068],"domain_scores_gemma":[0.9978845,0.0009420147,0.0001424816,0.0006385298,0.0002270264,0.0001654687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008268644,0.0002034434,0.0005292816,0.0001359015,0.0001313319,0.00001268686,0.001024975,0.0003273082,0.9890879,0.0001614818,0.00009879155,0.007459996],"study_design_scores_gemma":[0.0004975081,0.00003383,0.001267327,0.00009800767,0.00001971083,0.000002589953,0.0002282453,0.0004929489,0.9946912,0.0009256509,0.001572217,0.0001707694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902025,0.0007477665,0.0006021865,0.003424721,0.00001623762,0.0002617914,0.00005998105,0.00004506802,0.00463974],"genre_scores_gemma":[0.9977079,0.000963094,0.00007861725,0.00006912846,0.0001493184,0.0004776817,0.00001031011,0.00002423368,0.0005197213],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007505387,"threshold_uncertainty_score":0.5204125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1061794597338674,"score_gpt":0.3955781173763287,"score_spread":0.2893986576424613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}