{"id":"W2746525643","doi":"10.1128/mcb.00245-17","title":"Mice Deficient in <i>lysophosphatidic acid acyltransferase delta</i> ( <i>Lpaat</i> δ)/ <i>acylglycerophosphate acyltransferase 4</i> ( <i>Agpat4</i> ) Have Impaired Learning and Memory","year":2017,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Phosphatidic acid; Cardiolipin; AMPA receptor; Docosahexaenoic acid; Morris water navigation task; Phosphatidylethanolamine; Phosphatidylserine; Acyltransferase; Lysophosphatidic acid; Mitochondrion; Cell biology; Endocrinology; Internal medicine; Biochemistry; NMDA receptor; Receptor; Hippocampus; Phosphatidylcholine; Fatty acid; Phospholipid; Polyunsaturated fatty acid; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007006353,0.0005812824,0.0006365873,0.0001231158,0.0006496391,0.0001870332,0.0004862916,0.0004759294,0.00001855828],"category_scores_gemma":[0.0001786597,0.0005781278,0.0002095032,0.00008930633,0.0005645299,0.00002783074,0.0003244496,0.0004399971,0.000005463043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001345703,"about_ca_system_score_gemma":0.0001010001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000465287,"about_ca_topic_score_gemma":0.0001458215,"domain_scores_codex":[0.9968781,0.0003055478,0.0005678653,0.001200318,0.0001837418,0.0008643775],"domain_scores_gemma":[0.9986253,0.00003169077,0.0001849575,0.0007242222,0.00009312353,0.0003407165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003057082,0.00009500729,0.01166684,0.00006381451,0.00007187969,0.0001549433,0.0002188318,0.0000558732,0.9800054,0.0001869481,0.00003027054,0.007144528],"study_design_scores_gemma":[0.003689491,0.0003706928,0.0005154528,0.00004808835,0.0001049307,0.00008145502,0.0002485495,0.0001707027,0.9852007,0.0001841573,0.008690103,0.0006956827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9562899,0.0345747,0.007321022,0.0002565687,0.000309955,0.0004570357,0.00005139897,0.00003416686,0.0007052168],"genre_scores_gemma":[0.9933736,0.004240961,0.0005003515,0.001168152,0.0001533598,0.00006317266,0.0003159517,0.00008183489,0.0001026196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03708366,"threshold_uncertainty_score":0.999667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006196153514189712,"score_gpt":0.2314791793247931,"score_spread":0.2252830258106034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}