{"id":"W2746525643","doi":"10.1128/mcb.00245-17","title":"Mice Deficient in <i>lysophosphatidic acid acyltransferase delta</i> ( <i>Lpaat</i> δ)/ <i>acylglycerophosphate acyltransferase 4</i> ( <i>Agpat4</i> ) Have Impaired Learning and Memory","year":2017,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Phosphatidic acid; Cardiolipin; AMPA receptor; Docosahexaenoic acid; Morris water navigation task; Phosphatidylethanolamine; Phosphatidylserine; Acyltransferase; Lysophosphatidic acid; Mitochondrion; Cell biology; Endocrinology; Internal medicine; Biochemistry; NMDA receptor; Receptor; Hippocampus; Phosphatidylcholine; Fatty acid; Phospholipid; Polyunsaturated fatty acid; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002170573,0.001912072,0.0005575813,0.001473305,0.0003664739,0.0006993269,0.0007371683,0.001022054,0.004940579],"category_scores_gemma":[0.0002264532,0.0005372894,0.0007546124,0.0004846423,0.001001427,0.0004228225,0.0005923613,0.001824362,0.001864301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005260926,"about_ca_system_score_gemma":0.0003753629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001442218,"about_ca_topic_score_gemma":0.002041026,"domain_scores_codex":[0.9995499,0.0000332505,0.00007873498,0.0001480364,0.0001071401,0.00008290352],"domain_scores_gemma":[0.9991527,0.00005139023,0.0004180412,0.00006104074,0.00007027287,0.0002466136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002636311,0.00006185364,0.0003645513,0.0000411758,0.00002436739,0.000157833,0.00002754105,0.00005981087,0.9978006,0.0001569611,0.00007748352,0.000964085],"study_design_scores_gemma":[0.0001719942,0.0008655633,0.01389878,0.00005666655,0.0001846353,0.002952926,0.0002280874,0.001215614,0.9737087,0.000343112,0.006324934,0.00004877765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802554,0.0009140587,0.01043267,0.0003809224,0.000159359,0.00009945266,0.004712228,0.0008250566,0.002220858],"genre_scores_gemma":[0.9549167,0.001901977,0.01297713,0.000483238,0.00007613977,0.0003164785,0.006023833,0.0006787099,0.02262573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004940579,"threshold_uncertainty_score":0.01652783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006196153514189712,"score_gpt":0.2314791793247931,"score_spread":0.2252830258106034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}