{"id":"W2747268192","doi":"10.1139/cjpp-2017-0247","title":"Role of zinc oxide nanoparticles in alleviating hepatic fibrosis and nephrotoxicity induced by thioacetamide in rats","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Thioacetamide; Malondialdehyde; Chemistry; Lipid peroxidation; Superoxide dismutase; Internal medicine; Endocrinology; Creatinine; Nephrotoxicity; Oxidative stress; Kidney; Fibrosis; Hydroxyproline; Catalase; Pharmacology; Biochemistry; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001193582,0.0005541547,0.0004743377,0.0003673977,0.0001851359,0.0001585029,0.0002312521,0.0004280156,0.0005546974],"category_scores_gemma":[0.0001217618,0.0001820586,0.0003621363,0.0001464927,0.0002464431,0.0003012877,0.0001659054,0.0006100319,0.00008622146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001665897,"about_ca_system_score_gemma":0.0003576107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001640514,"about_ca_topic_score_gemma":0.002921991,"domain_scores_codex":[0.9999243,0.00001045649,0.000007228341,0.00001666288,0.00002164813,0.00001961864],"domain_scores_gemma":[0.9999088,0.000006707575,0.00003186873,0.000006308338,0.000014065,0.00003233831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001810921,0.0007046153,0.0006349534,0.000225593,0.00002948944,0.0001489588,0.00003410112,0.0001415712,0.988037,0.00008448726,0.00006770592,0.008080727],"study_design_scores_gemma":[0.0004197025,0.01513633,0.01028031,0.00004196038,0.0001753619,0.0003630494,0.0001109496,0.001482927,0.9688935,0.0002363501,0.002833626,0.00002602074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923719,0.003987357,0.002280183,0.0002398657,0.00006976217,0.00006731079,0.0001138686,0.00006767239,0.0008020779],"genre_scores_gemma":[0.9913151,0.003693514,0.002625378,0.0001229202,0.00002606786,0.0000685503,0.0001247347,0.000009055576,0.002014575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001640514,"threshold_uncertainty_score":0.003261924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0558757841390638,"score_gpt":0.3560475415122971,"score_spread":0.3001717573732333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}