{"id":"W2747644652","doi":"10.3389/fimmu.2017.01033","title":"Natural Killer (NK) Cell Education Differentially Influences HIV Antibody-Dependent NK Cell Activation and Antibody-Dependent Cellular Cytotoxicity","year":2017,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University Health Centre; McGill University","keywords":"Cytotoxicity; Antibody; Antibody-dependent cell-mediated cytotoxicity; Natural killer cell; Immunology; Cell; Lymphokine-activated killer cell; Chemistry; Human immunodeficiency virus (HIV); Cell biology; Biology; Interleukin 21; Immune system; T cell; In vitro; Monoclonal antibody; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001986685,0.0001669822,0.0004578861,0.00009783576,0.0001085675,0.0005400715,0.0001578113,0.0001903777,0.002905556],"category_scores_gemma":[0.000401097,0.0001017439,0.0001714476,0.00007178623,0.0001965095,0.0002648601,0.000231909,0.000709717,0.0004429572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001725729,"about_ca_system_score_gemma":0.0002634927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002712689,"about_ca_topic_score_gemma":0.0006056593,"domain_scores_codex":[0.9997467,0.00007178045,0.00002068724,0.00003667544,0.00002406156,0.0000999289],"domain_scores_gemma":[0.999887,0.00003417884,0.00001322288,0.00001344435,0.00001388022,0.00003830639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.007464061,0.0008892826,0.002490657,0.000204404,0.00002171132,0.0002197329,0.0001392357,0.0003036484,0.9675866,0.0005039129,0.0002691036,0.01990771],"study_design_scores_gemma":[0.001661343,0.02458226,0.04367747,0.00008766675,0.0002975045,0.001546938,0.0003939859,0.00294134,0.9106187,0.001038494,0.01311887,0.00003535945],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9964617,0.001095656,0.0003039823,0.00004110893,0.00003979824,0.00003254715,0.00004821505,0.00001737244,0.001959655],"genre_scores_gemma":[0.9979566,0.0004017492,0.000194217,0.00004288749,0.00001993402,0.00003363155,0.00006587314,0.00000534418,0.001279667],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002905556,"threshold_uncertainty_score":0.009720027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01574284747931019,"score_gpt":0.2888057126940438,"score_spread":0.2730628652147336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}