{"id":"W2747825855","doi":"10.1104/pp.17.00934","title":"Diacylglycerol Acyltransferase 1 Is Regulated by Its N-Terminal Domain in Response to Allosteric Effectors","year":2017,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Canola Producers Commission; Canada Research Chairs; Deutsche Forschungsgemeinschaft; Alberta Innovates Bio Solutions; Alberta Innovates - Health Solutions; Alberta Innovates - Technology Futures","keywords":"Allosteric regulation; Acyl-CoA; Allosteric enzyme; Myristoylation; Biochemistry; Diacylglycerol kinase; Acyltransferase; Chemistry; Coenzyme A; Enzyme; Stereochemistry; Biophysics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002819605,0.0002351505,0.0003198496,0.00006822245,0.0001538603,0.00003236907,0.000496312,0.0002255766,0.0000413073],"category_scores_gemma":[0.0001623652,0.0002005049,0.00008181003,0.00004379663,0.00008002374,0.000008622644,0.0001629516,0.00009409055,0.00007571226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001059654,"about_ca_system_score_gemma":0.00004456848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003486754,"about_ca_topic_score_gemma":0.00003305042,"domain_scores_codex":[0.9984636,0.0002695156,0.0002280351,0.0005339897,0.00009148855,0.0004133796],"domain_scores_gemma":[0.9990326,0.00005621385,0.00008121386,0.0006657421,0.00002499142,0.0001392439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00514082,0.00009015046,0.0006638317,0.00002000311,0.00003929922,0.00002001753,0.0001176697,0.000001309729,0.9900132,0.000002088252,0.002887593,0.00100401],"study_design_scores_gemma":[0.0008709991,0.0002844122,0.1023303,0.0000227308,0.00001366768,0.00001904753,0.000009416608,0.000006124347,0.8418217,0.000008692999,0.05436166,0.0002512635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983646,0.0001738419,0.00001021698,0.0004659627,0.0002502862,0.0002778888,0.0003894671,0.00001154076,0.00005621852],"genre_scores_gemma":[0.9983127,0.00006707042,0.00007725072,0.0007273195,0.0002119174,0.00004791813,0.0001937123,0.00002202484,0.0003401483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1481915,"threshold_uncertainty_score":0.8176352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007891144213390927,"score_gpt":0.2399814766844221,"score_spread":0.2320903324710311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}