{"id":"W2747825855","doi":"10.1104/pp.17.00934","title":"Diacylglycerol Acyltransferase 1 Is Regulated by Its N-Terminal Domain in Response to Allosteric Effectors","year":2017,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Canola Producers Commission; Canada Research Chairs; Deutsche Forschungsgemeinschaft; Alberta Innovates Bio Solutions; Alberta Innovates - Health Solutions; Alberta Innovates - Technology Futures","keywords":"Allosteric regulation; Acyl-CoA; Allosteric enzyme; Myristoylation; Biochemistry; Diacylglycerol kinase; Acyltransferase; Chemistry; Coenzyme A; Enzyme; Stereochemistry; Biophysics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006445714,0.000191182,0.0001864391,0.00006997625,0.0001364575,0.0001977014,0.000178693,0.0001724773,0.0005851249],"category_scores_gemma":[0.00008391686,0.00009710134,0.0001474625,0.00008483337,0.0001749381,0.0001111959,0.0001975211,0.0003170526,0.0004468456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003643273,"about_ca_system_score_gemma":0.00009974315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004126325,"about_ca_topic_score_gemma":0.0004616206,"domain_scores_codex":[0.9999391,0.000006561071,0.000003717765,0.00002191492,0.00001335484,0.00001541881],"domain_scores_gemma":[0.999936,0.000008745945,0.00001914262,0.00000653531,0.000007688537,0.00002178538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001039886,0.000007472612,0.000281401,0.00001697988,0.000001323306,0.00003613686,0.00001169343,0.00005512248,0.9989135,0.00004206174,0.00002829698,0.0005020558],"study_design_scores_gemma":[0.00004032653,0.0001097058,0.04086538,0.00001306852,0.00001454951,0.0006116144,0.00007163598,0.004412113,0.9479662,0.0002145388,0.005667824,0.00001300908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961119,0.001106672,0.001704435,0.00008883578,0.00001679111,0.000007836737,0.0001561048,0.00005150333,0.0007558865],"genre_scores_gemma":[0.9968643,0.0002946479,0.0009515337,0.00005604682,0.000006458339,0.00001238416,0.0004740087,0.0000100369,0.001330563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005851249,"threshold_uncertainty_score":0.002643406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007891144213390927,"score_gpt":0.2399814766844221,"score_spread":0.2320903324710311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}