{"id":"W2748005688","doi":"10.1016/j.exphem.2017.06.162","title":"Gfi1b regulates the level of Wnt/b-catenin signaling in hematopoietic stem cells and megakaryocytes","year":2017,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Wnt signaling pathway; WNT3A; Haematopoiesis; Biology; Stem cell; Transcription factor; Cell biology; Cancer research; Catenin; Molecular biology; Gene; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007617638,0.0001469115,0.000234383,0.00002451984,0.0001555043,0.00002189759,0.0002274024,0.000112895,0.00001200743],"category_scores_gemma":[0.000005475462,0.0001092304,0.00005436458,0.00001869191,0.0003021818,0.000006403386,0.0002142853,0.00004828308,0.000003638082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005611569,"about_ca_system_score_gemma":0.00001844623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001385467,"about_ca_topic_score_gemma":0.00005844965,"domain_scores_codex":[0.9992231,0.0000425915,0.0002122054,0.0002647884,0.00006480952,0.0001925302],"domain_scores_gemma":[0.9994676,0.00001842343,0.0001432094,0.0003185461,0.00001523879,0.00003697213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001087142,0.0003219794,0.01782115,0.000036117,0.00009288877,0.00002082196,0.000594939,0.000004275027,0.9752915,0.005132981,0.0001490646,0.0004256003],"study_design_scores_gemma":[0.001029577,0.0001500034,0.0009234168,0.00002336033,0.00001082875,0.00007125432,0.001006315,0.00001249449,0.9963473,0.0002604312,0.00005712037,0.0001078861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834307,0.01584768,0.000007648605,0.0001298307,0.00007847276,0.0001733919,0.000009082918,0.000003687255,0.0003195382],"genre_scores_gemma":[0.9994173,0.00006750763,0.0001809829,0.00004110582,0.00001462803,0.00003370561,0.000007425355,0.00001493969,0.0002223969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02105585,"threshold_uncertainty_score":0.4454286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03586108612305303,"score_gpt":0.2886703837633841,"score_spread":0.2528092976403311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}